Ceftriaxone improves motor function in a rat hemi-parkinsonian model: Potential to delay bilateral progression of motor deficits in Parkinson’s disease
Objective: This study sought to evaluate the impact of ceftriaxone, as a potential repurposed drug, in ameliorating motor decline in a unilateral rat 6-hydroxydopamine (6-OHDA)…Emerging motor dysfunction in those at-risk of Parkinson’s disease: 5-year follow-up of PREDICT-PD participants
Objective: To determine how motor features emerge over time in individuals estimated to be at higher risk of Parkinson’s disease (PD), compared with lower risk…Personal Kinetigraph and Deep Brain Stimulation with Parkinson’s Disease
Objective: To better understand the utility of a wearable wrist sensor in assessing and managing motor fluctuations in a population of patients with advanced Parkinson…Kinematic assessment of bradykinesia in patients with amyotrophic lateral sclerosis
Objective: To kinematically assess abnormalities of voluntary upper limbs movements in patients with amyotrophic lateral sclerosis compared to healthy subjects. To investigate possible relationships between…Movement Disorders Analysis Using a Deep Learning Approach
Objective: Using a deep learning inspired approach, we developed a tool to compute an objective score of bradykinesia. Background: Bradykinesia is defined as a motor…Patient experience interviews to inform a digital assessment of Parkinson’s disease
Objective: The aim of this study is to generate a conceptual framework that maps patient-relevant functional limitations to behavioral measures that can be captured with…A New Web-Based Tapping Test for Measuring Distal Bradykinesia in Parkinson’s Disease
Objective: 1. To develop a web-based test that objectively measures distal bradykinesia, 2. To validate the test by assessing PD patients and healthy controls, and…Robotic Assisted Arm Training in Parkinson’s disease rehabilitation: A pilot study
Objective: The aim and objective of this study was to evaluate whether robotic assisted arm training might improve upper limb function in patients with Parkinson’s…Inertial sensor-based kinematics in the differential diagnosis of Parkinson’s disease and atypical parkinsonisms
Objective: Assess the role of inertial sensors in the phenotyping and differential diagnosis of Parkinson’s Disease vs. Atypical Parkinsonisms Background: Wearable devices have been used…White Matter Changes and Early Cognitive Impairment in Parkinson’s Disease
Objective: Studying white matter changes in Parkinson's disease patients using diffusion tensor imaging; and its relation to cognition and motor symptoms impairment. Background: Cognitive dysfunction…
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