Comparison between clinical and kinematic assessment of bradykinesia
Objective: To compare the clinical and kinematic assessment of bradykinesia (movement slowness). Background: Bradykinesia may be present not only in Parkinson’s disease (PD), but also…A case of levodopa responsive parkinsonism due to methanol toxicity, an impact of COVID-19 crisis
Objective: To report the clinical course of secondary parkinsonism due to methanol toxicity with good levodopa responsiveness in the background of COVID-19 crisis. Background: The…Frequency dependent interindividual variability of the deep brain stimulation effect on upper-limb bradykinesia
Objective: To demonstrate that there are interindividual differences in the response of upper limb bradykinesia to subthalamic deep brain stimulation (STN-DBS) in patients with Parkinson’s…High-beta Oscillations Predict Outcome of Subthalamic Deep Brain Stimulation in Parkinson’s Disease
Objective: We evaluated whether low-β and high-β band activity recorded from the subthalamic nucleus (STN) region predicts efficacy of deep brain stimulation (DBS) in Parkinson's…Overnight stimulation: a new rescue strategy for deep brain stimulation-induced bradykinesia in dystonia?
Objective: We report the serendipity case of overnight stimulation for the management of stimulation-induced bradykinesia in two patients with generalized dystonia and clinically-effective pallidal deep…Validation of the PD Home Diary for Assessment of Motor Fluctuations in Advanced Parkinson’s Disease
Objective: To determine the validity of the Parkinson’s disease (PD) home diary for quantification of motor states in patients with advanced PD and motor fluctuations.…Motor Function Test Protocol for Parkinsonian Triad in Rodent Model of Parkinson’s Disease
Objective: To review motor deficits protocols and create a set of behavioural protocols that critically address the parkinsonian triad's quantification in Parkinson's disease models. Background:…Longitudinal Speech Changes In PD and the Relationship to Limb Bradykinesia and Rigidity
Objective: We tested the assumption that speech diadochokinesis (DDK) in Parkinson’s disease (PD) parallels motor system performances by evaluating DDK changes over 12-months and testing if DDK performance predicts limb bradykinesia and rigidity UPDRS scores. Background: Studies showing that speech DDK correlates with…‘Asymmetric thumb-index angle’ in PD: A new observation in an old disease
Objective: To report a novel sign on inspection in PD that is present throughout different dopaminergic states Background: Inspection is arguably one of the most…Wearable Devices in Movement Disorder Trials to Provide Objective Measures
Objective: To understand the validity of wearable devices in capturing objective motor and nonmotor symptoms of Parkinson’s Disease (PD) in addition to what has been…
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