“Striatal Hand Signs” and early diagnosis of Parkinson’s Disease: The “Monkey-Wrench Sign”.
Objective: To identify signs of hand deformations in PD patients with earlier diseases, and compare with intermediate and late phases patients. Background: “Striatal hand signs”,…Parkinson’s-disease risk variants are differentially associated with discrete phenotypic characteristics of Parkinson’s-disease at baseline.
Objective: Evaluate whether genetic risk variants for Parkinson’s disease discovered in case-control GWAS uniformly or differentially contribute to the clinical phenotype of PD. Background: Genetic…Motor Function Test Protocol for Parkinsonian Triad in Rodent Model of Parkinson’s Disease
Objective: To review motor deficits protocols and create a set of behavioural protocols that critically address the parkinsonian triad's quantification in Parkinson's disease models. Background:…Longitudinal Speech Changes In PD and the Relationship to Limb Bradykinesia and Rigidity
Objective: We tested the assumption that speech diadochokinesis (DDK) in Parkinson’s disease (PD) parallels motor system performances by evaluating DDK changes over 12-months and testing if DDK performance predicts limb bradykinesia and rigidity UPDRS scores. Background: Studies showing that speech DDK correlates with…‘Asymmetric thumb-index angle’ in PD: A new observation in an old disease
Objective: To report a novel sign on inspection in PD that is present throughout different dopaminergic states Background: Inspection is arguably one of the most…Wearable Devices in Movement Disorder Trials to Provide Objective Measures
Objective: To understand the validity of wearable devices in capturing objective motor and nonmotor symptoms of Parkinson’s Disease (PD) in addition to what has been…Slow Motion Analysis of Repetitive Tapping (SMART) test: measuring of bradykinesia in recently diagnosed Parkinson’s disease and idiopathic anosmia
Objective: To develop a quantitative method to track repetitive finger tapping movements and to compare people in the early stages of Parkinson’s disease (PD), healthy…Accelerometry to optimize optical flow measurement of repetitive finger tapping movements: A pilot study
Objective: To optimize optical flow (OF) measurement of repetitive finger tapping movements with the use of concomitant accelerometry in healthy volunteers. Background: Repetitive finger tapping…The Many Faces of Bradykinesia in Parkinson’s Disease : The Quantitative Analysis from A Keyboard Typing Test
Objective: To explore the characteristics of bradykinesia in PD via a keyboard typing test. Background: Bradykinesia is one of the cardinal symptoms in Parkinson’s disease…Association between actively and passively monitored hand gestures in early Parkinson’s disease
Objective: To determine the reliability and preliminary validity of passively acquired smartwatch-based sensor features of hand gestures in early Parkinson’s disease (PD). Background: Hand movements…
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