Tendency towards being a “Morning person” increases risk of Parkinson’s disease: evidence from Mendelian randomisation
Objective: To explore the causal relationship between circadian rhythm and Parkinson's disease (PD), and coffee consumption and PD, using Mendelian randomisation (MR). Background: Circadian rhythm…Identification of putative serum biomarkers for parkin-related Parkinson’s disease by metabolome analysis
Objective: Parkin is known as the causative gene of autosomal recessive familial Parkinson’s disease (parkin-PD). It remains unclear how parkin dysfunction associates with the dopaminergic…Caffeine as a Treatment for Parkinson’s Disease: A Randomized Controlled Trial (CafePD)
Objective: To assess the effects of caffeine on patients with Parkinson's disease. Background: Multiple studies have linked use of caffeine, an adenosine antagonist, to a…Integration of risk factors for PD in two large longitudinal cohorts
Objective: To derive a risk score for Parkinson’s disease (PD) based on lifestyle factors and family history and assess potential multiplicative and additive interaction between…Caffeinated Drinks, LRRK2 Genotype and PD
Objective: To determine the role of caffeine containing drinks on penetrance in LRRK2-associated PD Background: LRRK2 penetrance is reduced for PD [1]. Environment and/or other…Personality and addictive behaviours in prodromal and early Parkinson’s disease
Objective: To determine whether the personality changes demonstrated in established Parkinson's disease (PD) are found in the earliest stages of PD and the prodromal stage.…Headache in patients with Parkinsons disease: Pilot study results
Objective: Investigate the prevalence and characteristics of headache in PD patients, acknowledge the existing relation within the predominant laterality of the headache and side of…