Articles tagged "Chorea (also see specific diagnoses, Huntingtons disease, etc): Clinical features"

MDS Virtual Congress 2020
Remote and frequent assessment of Huntington’s disease in clinical trials: Strategies for assessing and accounting for the practice effect
A. Wolfer, F. Lipsmeier, R. Tortelli, F.B Rodrigues, L.M Byrne, C. Simillion, T. Kilchenmann, A. Bamdadian, S.A Schobel, E.J Wild, M. Lindemann (Basel, Switzerland)
Objective: To assess the impact of task repetition on performance in digital assessments on Huntington’s disease (HD) and establish the number of practice test iterations…
MDS Virtual Congress 2020
HD Constellation: A novel patient-centred approach to enriching clinical datasets by combining medical record chart review and Enroll-HD
K. Belendiuk, J.P Sacksteder, X. Sanii, E. Neacy, J. Levey, E. Korner, R. Houghton, G. Yohrling (South San Francisco, CA, USA)
Objective: HD Constellation aims to create a dataset providing a longitudinal view of the Huntington’s disease (HD) course, based on physician-provided medical records in the…
MDS Virtual Congress 2020
Biological and Clinical Manifestations of Huntington’s disease in Gene Carriers Very Far from Predicted Onset: The Young Adult Study
P. Zeun, R. Scahill, K. Osborne-Crowley, E. Johnson, S. Gregory, C. Parker, J. Lowe, A. Nair, C. O'Callaghan, C. Langley, M. Papoutsi, P. McColgan, C. Estevez-Fraga, K. Fayer, H. Wellington, F. Rodrigues, L. Byrne, A. Heselgrave, H. Hyare, C. Sampaio, H. Zetterberg, H. Zhang, E. Wild, G. Rees, T. Robbins, B. Sahakian, D. Langbehn, S. Tabrizi (London, United Kingdom)
Objective: To perform a deep phenotyping of a Huntington’s Disease (HD) cohort further from onset than previously studied to establish when disease related markers first…
MDS Virtual Congress 2020
Longitudinal Utility of the Montreal Cognitive Assessment and Mini Mental State Exam in Huntington’s disease (HD)
I. Beltran-Najera, J. Corey-Bloom, C. Snell, A. Smirnova, P. Gilbert (San Diego, CA, USA)
Objective: Neuropsychological assessments are useful tools for examining and tracking cognitive impairment in individuals with neurological disorders; however, a full neuropsychological battery is not realistic…
MDS Virtual Congress 2020
Defining time and anatomical specificity of basal ganglia white matter loss in premanifest Huntington’s disease
P. Zeun, P. McColgan, T. Dhollander, S. Gregory, E. Johnson, M. Papoutsi, R. Scahill, G. Rees, S. Tabrizi (London, United Kingdom)
Objective: To identify when white matter connections first begin to degenerate in HD and which connections are most susceptible to early degeneration. Background: Huntington’s disease…
MDS Virtual Congress 2020
Genetic analysis of Huntington’s Disease in a Brazilian Amazonian population
D. Brito, M. Della Coletta, G. Ferreira, L. Amorim, S. Souza, S. Peixoto, C. Rezende (Manaus, Brazil)
Objective: Characterize genetically a series of cases of patients with Huntington’s disease and their family members at risk in the city of Manaus, capital of…
MDS Virtual Congress 2020
7 Tesla MRI investigation of cortical thickness in patients with Huntington’s disease and age-matched healthy controls
M. Morrison, A. Jakary, S. Avadiappan, J. Tallakson, J. Glueck, A. Nelson, K. Possin, C. Dietiker, M. Geschwind, C. Hess, L. Lupo (San Francisco, CA, USA)
Objective: Evaluate cortical thickness in Huntington's disease (HD) using 7 Tesla (T) MRI. Background: There are currently no effective disease-modifying therapies for HD. In order…
MDS Virtual Congress 2020
Modelling Huntington’s disease diagnosed prevalence from diagnosed incidence and survival time
V. Crowell, R. Houghton, F. Squitieri, A. Tomar, T. Fernandes (Basel, Switzerland)
Objective: To develop an epidemiological model of manifest Huntington’s disease (HD) to estimate international HD diagnosed prevalence by Shoulson–Fahn Total Functional Capacity (TFC)-based Stage based…
MDS Virtual Congress 2020
Apathy as a non-motor symptom(NMS) in patients with Parkinson’s disease(PwPD) and patients with Huntington’s disease(PwHD) in Tomsk, Russia
M. Nikitina, V. Alifirova, K. Nurzhanova, N. Center, N. Zhukova (Tomsk, Russian Federation)
Objective: The aim is to evaluate and compare the apathy profile in PwHD and PwPD, using the same clinical criteria to assess the severity of…
2019 International Congress
Homozygous Huntington’s disease with two reduced penetrance alleles: A Case Report
K. Grimm, C. Zühlke, C. Gerloff, S. Zittel (Hamburg, Germany)
Objective: To clinically characterize a Huntington's disease patient with two reduced penetrance alleles. Background: Huntington's disease (HD) is an autosomal dominant neurodegenerative disorder manifesting with…