MDS Abstracts

Abstracts from the International Congress of Parkinson’s and Movement Disorders.

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Articles tagged "Chorea (also see specific diagnoses, Huntingtons disease, etc): Treatment"

  • MDS Virtual Congress 2020

    Healthcare resource utilisation and costs among patients with versus without Huntington’s disease in the US population

    A. Exuzides, T.M To, I. Abbass, A. Surinach, R. Fuller, J. Luo (South San Francisco, CA, USA)

    Objective: Compare the marginal healthcare resource utilisation (HRU) and costs between US patients with Huntington’s disease (HD) and non-HD controls. Background: HD is a genetic,…
  • MDS Virtual Congress 2020

    Deutetrabenazine for Huntington’s disease chorea—A Single Center’s Experience

    D. Fischer, R. Caskey, M. Dean, V. Sung (Birmingham, AL, USA)

    Objective: To evaluate real-world use and outcomes with deutetrabenazine for Huntington’s disease. Background: Grade A evidence for Huntington’s disease chorea treatment includes tetrabenazine and deutetrabenazine.…
  • MDS Virtual Congress 2020

    Evaluation of the Safety of Deutetrabenazine at Higher Doses to Treat Chorea in Huntington’s Disease

    S. Frank, C. Vaughan, D. Stamler, D. Oakes, M. Davis, N. Gross, M. Gordon, J.M Savola, M. Wieman, S. Eberly, E. Kayson, J. Whaley, J. Goldstein, C. Testa (Boston, MA, USA)

    Objective: To evaluate the safety and tolerability of deutetrabenazine >48 mg/d compared to ≤48 mg/d to treat Huntington’s disease (HD)–associated chorea in ARC-HD. Background: In…
  • MDS Virtual Congress 2020

    VMAT 2 inhibitor and Antipsychotic use in Individuals with Huntington’s Disease

    E. Furr Stimming, L. Zhu, N. Pessoa Rocha (Houston, TX, USA)

    Objective: To retrospectively investigate whether the concomitant use of VMAT2 inhibitors and antipsychotics in individuals with Huntington's disease (HD) is associated with an increased occurrence…
  • MDS Virtual Congress 2020

    Cytokines and Brain Specific Antibodies in Experimental Cellular and Molecular Treatment of Huntington’s Diseases

    D. Labunskiy, S. Kiryukhina, V. Podsevatkin (Saransk, Russian Federation)

    Objective: Huntington’s Disease (HD) is a severe neurodegenerative disorder main pathogenic factor is CAG repeats in a suffered patients genome. Experimental therapy on the model…
  • MDS Virtual Congress 2020

    A longitudinal PET study to assess the state of microglia activation in a Phase 2 study of Laquinimod as a treatment for Huntington’s disease (LEGATO-HD)

    A.A Roussakis, M. Gennaro, M.F Gordon, R. Reilmann, B. Borowsky, G. Rynkowski, J.M Savola, M.R Hayden, R. Gunn, S. Tabrizi, P. Piccini (London, United Kingdom)

    Objective: To assess in vivo in Huntington’s disease (HD) changes in microglia activation state, due to treatment with laquinimod, as reflected by changes in 11C-PBR28…
  • MDS Virtual Congress 2020

    Biological and Clinical Manifestations of Huntington’s disease in Gene Carriers Very Far from Predicted Onset: The Young Adult Study

    P. Zeun, R. Scahill, K. Osborne-Crowley, E. Johnson, S. Gregory, C. Parker, J. Lowe, A. Nair, C. O'Callaghan, C. Langley, M. Papoutsi, P. McColgan, C. Estevez-Fraga, K. Fayer, H. Wellington, F. Rodrigues, L. Byrne, A. Heselgrave, H. Hyare, C. Sampaio, H. Zetterberg, H. Zhang, E. Wild, G. Rees, T. Robbins, B. Sahakian, D. Langbehn, S. Tabrizi (London, United Kingdom)

    Objective: To perform a deep phenotyping of a Huntington’s Disease (HD) cohort further from onset than previously studied to establish when disease related markers first…
  • MDS Virtual Congress 2020

    A Rare Disease with Atypical Clinical And Imaging Findings: Anti Lgi-1 Encephalitis

    O. Yilmaz Kusbeci, I. Keskin, M. Gedizlioglu (Izmir, Turkey)

    Objective: We present a case that will raise awareness about the disease with atypical clinical and rich imaging findings that has benefited greatly from intensive…
  • MDS Virtual Congress 2020

    Hyperpolarization of the subthalamic nucleus alleviates hyperkinetic movement disorders

    C.H Tai, S.H Tseng, T.R Wang, M.T Hsu, C-C. Kuo (Taipei, Taiwan)

    Objective: We test the hypothesis of modulating subthalamic neuronal firing pattern via injection of hyperpolarizing current as an effective treatment for hyperkinetic movement disorders. Background:…
  • MDS Virtual Congress 2020

    Real-World Deutetrabenazine Dosing Patterns in Patients With Huntington’s Disease or Tardive Dyskinesia

    R. Ayyagari, A. Wilhelm, J. Alexander, N. Chaijale, V. Garcia-Horton, F. Devine, B. Carroll (Boston, MA, USA)

    Objective: To evaluate real-world treatment patterns and adherence to deutetrabenazine (DTBZ) in patients with Huntington’s disease (HD) or tardive dyskinesia (TD). Background: DTBZ is a…
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