Steroid responsive chorea in Moyamoya disease: illustrative cases
Objective: To report the rapid reduction of disabling chorea in two cases of pediatric Moyamoya disease with pulse steroid therapy. Background: The common clinical presentation…Internal pallidum stimulation reduces mobile generalized dystonia in Wilson’s disease
Objective: Globus Pallidus internus (GPi) deep brain stimulation (DBS) is established in treatment of dystonia. We evaluated safety and efficacy of bilateral GPi stimulation in…Feasibility and acceptability of a therapist-delivered physical activity coaching intervention for people with premanifest and early stage Huntington’s Disease and Parkinson’s Disease
Objective: To assess the feasibility, acceptability, and preliminary efficacy of the Pre-Active PD and HD interventions for increased physical activity (PA) engagement in people with…Electroconvulsive Therapy (ECT): An Effective Option for the Treatment of Medication-Resistant Psychiatric Symptoms in Huntington’s Disease: A Case Series and Review of the Literature
Objective: Through a single site case series, we investigate the use and effectiveness of electroconvulsive therapy (ECT) for the treatment of refractory psychiatric symptoms in…The History of Huntington Disease Description in Russia
Objective: The report provides detailed material on the history of the description of Huntington's disease (HD) in Russia. The first, unknown to a wide audience,…Sydenham’s Chorea: Realities and Challenges in Sub-Saharan Africa
Objective: The aim of this study was to describe the epidemiological, clinical, paraclinical and evolutive aspects of Sydenham's chorea. Background: Sydenham's chorea is a rare…Pallidotomy for Intractable Hemichorea in Sudden Hyperglicemic Pituitary Adenoma Patient
Objective: To prove that pallidotomy can be an alternative therapy for intractable chorea. Background: A 61 year old woman come with complaint sudden irregular movement…A randomized, double-blind, placebo-controlled Phase II Efficacy and Safety Study of the PDE10A inhibitor PF-02545920 in Huntington Disease (AMARYLLIS)
Objective: To assess efficacy on motor function, safety and tolerability of the phosphodiesterase-10A inhibitor PF-02545920 in Huntington disease (HD). Conclusion: PF-02545920 was generally safe and…Treating Huntington’s Disease using a holistic approach
Objective: Huntington’s disease (HD) is a fatal genetic disorder that causes the progressive breakdown of nerve cells in the brain. It deteriorates a person’s physical…Cognitive Reserve and Physical Activity Modulate Functional Brain Re-organisation in Premanifest Huntington’s Disease: Preliminary Evidence
Objective: In this study, for the first time we examined the relationship between cognitive reserve, sleep quality and current level of physical exercise and functional…
Abstracts from the International Congress of Parkinson’s and Movement Disorders.