Expanding the Childhood Spectrum of Dentatorubral–pallidoluysian Atrophy: Neuropsychiatric and Motor Phenotypes in Four Siblings
Objective: We aim to characterize the striking clinical heterogeneity of movement, epileptic, and neuropsychiatric symptoms in a cohort of four siblings with genetically confirmed DRPLA.…Diffusion MRI Evidence of Cerebellar Involvement in Cognitive Dysfunction in Parkinson’s Disease
Objective: To determine whether cerebellar axonal microstructural abnormality is associated with cognitive performance in PD. Background: Cognitive impairment in Parkinson’s disease (PD) often affects executive…Verbal Communication After Subthalamic Nucleus Deep Brain Stimulation
Objective: To evaluate the contribution of motor speech, language, and cognition to communication changes after subthalamic nucleus deep brain stimulation (STN-DBS) in people with Parkinson’s…Optimal and invariant hierarchical cognitive indices in the Parkinson’s Progression Markers Initiative
Objective: To expand cognitive indices derived from PPMI cognitive battery (PPMI-CB) by testing hierarchical models and measurement invariance across pertinent groups. Background: Parkinson’s can cause…Fibrinogen and CFAH as putative biomarkers for Parkinson’s disease
Objective: To examine the levels of putative biomarkers FIB, CFAH, gelsolin (GSN), α-syn and phosphorylated-α-syn in PD serum. To localize and quantify FIB and CFAH in…Adult hippocampal neurogenesis and cognitive and neuropsychiatric symptoms in Parkinson’s disease: the MemHiN study
Objective: To examine associations between serum-derived adult hippocampal neurogenesis (AHN)1 markers and cognitive and neuropsychiatric symptoms in Parkinson’s disease (PD), and to explore whether a…The Effect of Depression on the Cognitive Phenotype in a Group of Patients Diagnosed with Idiopathic Parkinson’s Disease Without Dementia.
Objective: To investigate the impact of depression on cognitive functioning in a group of older adults without dementia. Background: Parkinson’s disease (PD) is a neurodegenerative…Effectiveness of Acupuncture for Parkinson’s Disease with Mild Cognitive Impairment A Randomized Clinical Trial
Objective: To evaluate the efficacy and safety of acupuncture for PD-MCI, and improve the credibility of acupuncture research evidence through employing a sham acupuncture device…Online Assessments Measure Motor and Cognitive Progression in People with and without Parkinson’s Disease
Objective: To evaluate longitudinal progression in online participant reported outcomes (PROs) among people with Parkinson’s disease (PD), prodromal PD, and healthy controls. Background: Collecting PROs…Increased Pre-Alpha EEG Functional Connectivity Forecasts Future Cognitive Decline in Parkinson’s Disease
Objective: To evaluate whether resting-state EEG functional connectivity (rsEEG-FC) forecasts cognitive decline three years later in Parkinson’s disease (PD). Background: Cognitive performance and trajectories of…
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