A Prospective Study of the Effects of Deep Brain Stimulation on Constipation and Olfaction in Parkinson Disease
Objective: To investigate the effects of subthalamic nucleus deep brain stimulation (STN-DBS) on constipation and olfaction in patients with Parkinson disease (PD). Background: STN-DBS is…Gastrointestinal microbiome in Parkinson’s disease in a Bavarian cohort
Objective: Our goal was to evaluate, whether gut microbiota are altered in a Southern German PD cohort. In addition, we assessed changes in the microbiome…A randomized double-blind placebo-controlled trial of probiotics for constipation in Parkinson’s disease
Objective: To investigate the effects of probiotics on constipation in PD, using a randomized controlled trial (RCT) design Background: Non-motor symptoms (NMS) cause significant disability…The Gut Microbiota in a Canadian Parkinson’s Disease Cohort
Objective: To compare the gut microbiota between PD patients and matched controls in a Canadian cohort and to examine correlations between microbes and disease parameters…Characterization of the gastrointestinal dysfunction in mice overexpressing the human mutation (A53T) of alpha-synuclein
Objective: The aim of this study was to determine if mice overexpressing the human mutation of alpha-synuclein develop gastrointestinal (GI) dysfunction, and to understand the…Striatal dopamine transporter availability changes reflect gastrointestinal dysautonomia severity in early Parkinson’s disease
Objective: To test the hypothesis that constipation and gastrointestinal (GI) dysautonomia may be correlated with nigrostriatal dopaminergic (DA) dysfunction in PD. Background: Constipation is a…Early gastrointestinal dysfunction is predictive of faster progression in Parkinson’s disease
Objective: To evaluate whether constipation at time of diagnosis has prognostic significance in terms of motor and cognitive progression in PD. Background: There is evidence…Pain is correlated with other motor and non-motor symptom in Parkinson’s disease
Objective: Study pain occurrence and appearance in Parkinson’s disease (PD), and its relationship with other motor and non-motor symptoms like constipation and footsteps. Background: The…Gut microbiota geography in Parkinson’s disease in the world
Objective: The 16 rRNA analysis and the shotgun metagenome analysis in our cohort were compared with 5 previous reports by others. Background: In PD patients,…Objective intestinal dysfunction in REM sleep behaviour disorder
Objective: To study objectively measured intestinal function, defined by intestinal volume, transit times, and colonic motility patterns in patients with idiopathic REM sleep behaviour disorder…
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