Characteristics of lower gastrointestinal tract dysfunction in patients with Parkinson disease
Objective: To evaluate the characteristics of lower gastrointestinal tract dysfunction in patients with Parkinson disease (PD). Background: Lower gastrointestinal tract dysfunction is common in patients…Characterization of the gastrointestinal dysfunction in the 6-hydroxydopamine rat model of Parkinson’s disease
Objective: To characterize the gastrointestinal (GI) phenotype in the 6-hydroxydopamine (6OHDA) rat model of Parkinson’s disease (PD). Background: GI dysfunction, such as prolonged GI transit…A Prospective Study of the Effects of Deep Brain Stimulation on Constipation and Olfaction in Parkinson Disease
Objective: To investigate the effects of subthalamic nucleus deep brain stimulation (STN-DBS) on constipation and olfaction in patients with Parkinson disease (PD). Background: STN-DBS is…Gastrointestinal microbiome in Parkinson’s disease in a Bavarian cohort
Objective: Our goal was to evaluate, whether gut microbiota are altered in a Southern German PD cohort. In addition, we assessed changes in the microbiome…Path to Prevention (P2P) – Developing a Prodromal PD Progression Biomarker Program
Objective: The overall objective of the Path to Prevention (P2P) initiative is to identify clinical, imaging, and biologic markers of progression during the prodromal phase…The Dutch Parkinson and Microbiome Study (DUPARM): Gut Microbiome Composition of Treatment-Naïve De Novo Parkinson’s Disease Patients
Objective: To establish the gut microbiome composition of de novo Parkinson’s disease (PD) patients with no history of dopaminergic medication use. Background: PD is often…Comprehensive clinico-pathophysiological assessment of constipation in Parkinson’s disease
Objective: To perform a comprehensive assessment of constipation in Parkinson’s disease (PD) using various complementary diagnostic techniques to elucidate its pathophysiology and improve its symptomatic…The ultrasonographic assessment of vagus nerve atrophy comparison with autonomic dysfunction in Parkinson’s disease
Objective: To investigate the relationship between vagus nerve atrophy and clinical manifestation in Parkinson’s disease (PD). Background: PD is the progressive neurodegenerative disease and causes…A randomized double-blind placebo-controlled trial of probiotics for constipation in Parkinson’s disease
Objective: To investigate the effects of probiotics on constipation in PD, using a randomized controlled trial (RCT) design Background: Non-motor symptoms (NMS) cause significant disability…The Gut Microbiota in a Canadian Parkinson’s Disease Cohort
Objective: To compare the gut microbiota between PD patients and matched controls in a Canadian cohort and to examine correlations between microbes and disease parameters…
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