The effect of uni- and bilateral thalamic deep brain stimulation on speech in patients with essential tremor: Acoustics and intelligibility
Objective: In this study, we investigate the effect of VIM-DBS on speech in ET patients. We compare how uni- vs. bilateral DBS contributes to the…Influence of different spike sorting algorithms on the detection of single unit spiking activity in the subthalamic nucleus of patients with Parkinson’s disease
Objective: To determine the most suitable spike sorting algorithm for intraoperatively recorded extracellular currents in the subthalamic nucleus (STN) of patients with Parkinson's disease (PD).…Temporal dynamics of pallidal low-frequency oscillations in dystonia
Objective: To assess the occurrence and volatility of 4-12 Hz oscillations in local field potentials (LFPs) recorded in the internal globus pallidus (GPi) of dystonia…Beyond 30 years of Parkinson’s disease: A comprehensive characterization of long-surviving patients
Objective: To analyze the features of very late stage Parkinson's disease (PD) in a selected group of patients treated with bilateral subthalamic nucleus DBS (STN-DBS),…Objectivisation of postural disorders in patients with Parkinson’s disease during the screening stage for DBS
Objective: Objectivisation of degree of postural disorders in PD patients during the screening stage for DBS. Background: The neurosurgical treatment of Parkinson's disease (PD) using…Clinical outcome of subthalamic deep brain stimulation in Parkinson’s disease – The Helsinki experience
Objective: To evaluate the efficacy and adverse effects of subthalamic deep brain stimulation (STN-DBS) in patients with advanced Parkinson's disease (PD) and the possible correlation…Identification of unique metabolite signatures in post-mortem DBS human tissue using LC-HRMS
Objective: Metabolomics is applied to the study of metabolic as well as neurodegenerative diseases. We propose to utilize this technique to detect metabolic changes from…A dopamine-dependent activity of the STN in the control of balance in Parkinson’s disease
Objective: To investigate the activity of the subthalamic nucleus (STN), and its relation to nigro-striatal dopaminergic denervation, in control of balance in Parkinson's disease (PD).…Cognitive outcome in the patients with Parkinson’s disease one year after subthalamic implants in Taiwan
Objective: To demonstrate cognitive outcome after subthalamic deep brain stimulation(DBS) in the patients with Parkinson's disease(PD) in Taiwan. Background: Deep brain stimulation of the subthalamic…A case of thalamic malignant glioma formation in a patient with STN-DBS for Parkinson’s disease
Objective: We present a case of development of malignant glioma (glioblastoma multiforme) in the area adjacent to electrostimulation zone in a patient with chronic STN-DBS,…
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