Keeping patients out of care facilities— clozapine rescues Parkinson’s patients with troublesome psychosis unresponsive to quetiapine and pimavanserin.
Objective: We describe a single-center cohort of Parkinson patients in crisis with troublesome psychosis unresponsive to quetiapine and pimavanserin, who were rescued by treatment with…Combined GWAS of Dementia with Lewy Bodies, REM-Sleep Behavior Disorder, Parkinson’s Disease and Alzheimer’s Disease
Objective: To identify genetic variants that are either shared between or specific for Dementia with Lewy Bodies (DLB), REM Behavior Disorder (RBD), Parkinson’s disease (PD)…Utility of quantitative EEG during sleep as a potential biomarker of Lewy body disease progression
Objective: Objective: To assess whether progression from isolated REM sleep behaviour disorder (iRBD), established Parkinson’s disease (PD) and Dementia with Lewy bodies (DLB) are accompanied…Are patients presenting earlier in time? Secular changes in REM sleep behavior disorder
Objective: To determine if secular changes occur in REM sleep behavior disorder (RBD). Background: RBD is the strongest clinical marker of prodromal synucleinopathy, and provides…Myocardial sympathetic denervation biomarkers for early detection of prodromal DLB
Objective: Because of the time course of detecting DLB symptoms and signs, DLB is poorly diagnosed and hardly differentiate from AD, especially in early stage…Potentially inappropriate medication useage among patients newly diagnosed with dementia with Lewy bodies
Objective: Investigate the use of potentially inappropriate medications (PIM) among patients newly diagnosed with dementia with Lewy bodies (DLB). Background: PIM, including anticholinergics, are associated…Predicting cognitive decline using neuropsychiatric symptoms in prodromal Lewy body disease.
Objective: To investigate the influence of neuropsychiatric symptoms (NPS) on early cognitive decline in patients with Lewy body disease (LBD). Background: NPS in LBD, including…Plasma p-tau181 is increased in Lewy body dementia and relates to cognitive performance
Objective: To compare plasma p-tau181 concentration in Parkinson’s disease (PD), Lewy body dementia (LBD) and healthy controls and to examine the relationship between ptau-181 concentration…Lewy body disease clinical subgroups present similar disease progression rates
Objective: To characterize LBD clinical subgroups and identify possible differences in disease progression. Background: Patients with Lewy body disease (LBD) present a wide variety of…Survival and progression in GBA-associated dementia with Lewy bodies
Objective: To assess the impact of GBA mutations and APOE polymorphisms on progression and survival in a cohort of Ashkenazi Jewish (AJ) patients with DLB.…
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