Impact of Cognitive Profile on Impulse Control Disorders Presence and Severity in Parkinson’s Disease
Objective: To investigate whether Parkinson’s disease (PD) cognitive states and phenotypes are associated with changes in prevalence and severity of Impulse control disorder (ICD). Background:…Cortical FDG-PET patterns predict long-term motor progression and disability milestones in Parkinson’s disease
Objective: To evaluate the accuracy of single-subject FDG-PET in predicting motor and cognitive long-term progression in Parkinson's disease Background: The progression of Parkinson's disease is…Introduction of an Assessment Toolkit Increases the Rate of DLB Diagnosis
Objective: To assess whether diagnostic rates of both Parkinson’s disease dementia (PDD) and dementia with Lewy bodies (DLB) could be increased by the introduction of…A phase IIa trial studying the safety and tolerability of IRL752 in patients with Parkinson’s disease dementia
Objective: The primary objective was to investigate the safety and tolerability of IRL752 in PD patients with dementia in a randomized controlled trial. Secondary outcome…Characteristic Parkinsonism Questionnaire for the Discrimination of Parkinson’s Disease Dementia from Vascular Dementia
Objective: We have designed a characteristic 8-item parkinsonism questionnaire for the screening of motor dysfunction due to Lewy body dementia (LBD). We aim to test…Role of Alzheimer’s Disease Genetic Risk Variant rs9331896 in Cognitive Decline in Parkinson’s Disease
Objective: To investigate whether susceptibility loci for Alzheimer's disease (AD) are associated with rates of longitudinal cognitive decline in Parkinson’s disease (PD). Background: Parkinson’s disease…Clinico-pathological Findings In Autopsy Cases With Non-Specific Glial Tauopathy
Objective: Determine Clinico-pathological correlates of aging-related tau astrogliopathy (ARTAG). Background: Aging-related tau astrogliopathy (ARTAG) appears to be a morphological spectrum of astroglial pathology mostly seen in…An Informant-based Simple Questionnaire for Executive Function Assessment in Dementia with Lewy Bodies and Alzheimer’s Disease
Objective: The aim of this study was to investigate and compare executive dysfunction by using a newly designed informant-based simple questionnaire among patients with DLB…Spontaneous Pisa Syndrome in a Patient with Early-onset Alzheimer’s Disease
Objective: We report a case of early-onset AD where spontaneous Pisa syndrome predominated. Background: Pisa syndrome, an involuntary, reversible lateral deviation of the trunk, was…In vivo and In vitro study of 17β estradiol against amyloid beta neurotoxicity in synaptosomes of aging female rats : A therapeutic potential drug for Alzheimer’s disease
Objective: The aim of the present study was to determine the effects of neuropeptide, neurokinin B (NKB) and amyloid beta fragment Aβ (25-35) on 17β…
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