Genetic risk factors of dementia and psychosis in Parkinson’s disease
Objective: We investigated the impacts of apolipoprotein E (APOE) genotype and glucocerebrosidase gene (GBA) heterozygote mutations on dementia or psychosis in Parkinson's disease (PD). Background:…Olfactory performance and resting state functional connectivity in non-demented drug naïve patients with Parkinson’s disease
Objective: We investigated the pattern of resting state functional connectivity in patients with PD according to olfactory performance to elucidate olfactory-dependent cortical-subcortical functional networks. Background:…Speech prosody impairment predicts cognitive decline in Parkinson’s disease
Objective: We assessed whether baseline speech prosodic parameters, alone or in combination with other predominantly non-dopaminergic symptoms may predict global cognitive decline as measured by…Effect of nelotanserin on objective sleep parameters in a phase 2 study in patients with insomnia
Objective: To understand the effects of nelotanserin on objective sleep parameters in a phase 2 study in patients with primary insomnia. Background: Nelotanserin is a…Comparison of cognitive and neuropsychological manifestations in patients with progressive supranuclear palsy (Psp) and Parkinson’s disease
Objective: 1) To compare the cognitive and neuropsychological manifestations between the patients with PSP and PD. 2) To find out the severity of caregivers distress…Next-generation profiling to identify the molecular etiology of Parkinson’s disease dementia
Objective: To identify novel gene regulatory events associated with Parkinson's disease with dementia (PD-D). Background: PD-D is associated with the spread of degenerative pathology to…Depressive disorders in Parkinson’s disease and Alzheimer’s disease
Objective: Our primary aim was to study of the clinical characteristics of DD in patients with AD and PD. Background: The problem of a combination…Association between urine protein/creatinine ratio and cognitive dysfunction in Parkinson’s disease
Objective: We investigated the relationship between proteinuria and cognitive dysfunction in patients with Parkinson's disease. Background: Impaired renal function and proteinuria have been associated with…How accurate is the prediction of driving ability in a Parkinson’s clinic setting?
Objective: To determine whether routine clinical assessment (motor examination, cognitive assessment and global clinical impression) accurately predicts the ability of People with Parkinson's (PwP) to…A novel phenotype of amyloid precursor protein (APP) mutation presenting with dementia, and symptoms of both progressive supranulcear palsy (PSP) and multisystem atrophy (MSA)
Objective: To describe the novel phenotype of a patient with an amyloid precursur protein (APP) mutation presenting with dementia and symptoms of both progressive supranulcear…
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