HGprt deficient brain RNA expression patterns reveal specific abnormalities related to neuronal function in a mouse model of Lesch-Nyhan disease.
Objective: To determine the effect of hypoxanthine guanine phosphoribosyl transferase (HGprt) deficiency on mouse brain RNA expression patterns in multiple brain areas, during embryonic development…HGprt deficiency affects early brain development in vivo in a mouse model of Lesch-Nyhan disease
Objective: To determine the effects of hypoxanthine guanine phosphoribosyl transferase (HGprt) deficiency on early brain development in vivo, in a HPRT1-deficient mouse model. Background: Lesch-Nyhan…Special features of parkinsonism with congenital anomalies of cerebral vessels
Objective: To study the features of the flow of parkinsonism with congenital anomalies of cerebral vessels. Background: Analysis of the study of neurological status, data…Evaluation of nigral neuronal apoptosis during postnatal development and adulthood of mice strains with differential sensitivity to MPTP
Objective: Compare nigral neurons in C57BL/6J, CD-1 and their F1 crossbreds with respect to developmental apoptosis in the nigra during postnatal and to assess MPTP-induced…Gender-dependent improvement in the survival of Parkinson’s disease patients in Finland
Objective: To longitudinally investigate the overall survival (OS) of a large cohort of Parkinson's disease (PD) patients. Background: While there is evidence of increasing incidence,…Study on feasibility to develop a central nervous system (CNS) Leucine-rich repeat kinase 2 (LRRK2) PET tracer
Objective: To assess feasibility of developing a CNS LRRK2 PET tracer. Background: LRRK2 enzyme belongs to the leucine-rich repeat kinase family. Pathogenic mutations in the…The pulmonary function and respiratory muscle strength tests of elderly people with Parkinson’s disease: A two-year observational study
Objective: To follow for two years pulmonary function and respiratory muscle strength tests of elderly people with Parkinson's disease (PD). Background: Respiratory disorders are common…STN DBS – A study of frequency of gait (fog) in Parkinson’s disease
Objective: In search of new techniques to help improve lifestyle of Parkinson`s diseased conditions (PDs), a wireless technique is proposed to identify freeze, reduce freeze,…A framework to facilitate competence in practice for Parkinson’s Disease Nurse Specialists in the United Kingdom
Objective: To determine if the current Parkinson's Disease Nurse Specialist (PDNS) competency framework 2nd Edition 2008 (1) for nurses working in the management of Parkinson's…An evaluation of the availability and format of information provided to patients who have a new diagnosis of Parkinson’s disease (PD)
Objective: To evaluate if the information provided to a person with Parkinson’s (PwP) is relevant and appropriate for that individual. To also consider the need…
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