Seronegative Autoimmune Encephalitis Presenting as Hemichorea: A Case Report
Objective: To report a case of hemichorea due to seronegative autoimmune process. Background: Autoimmune encephalitis can present with diverse hyperkinetic or hypokinetic phenomenology. Autoimmune movement…Higher Dopaminergic Sensitivity Underlies Dyskinesia Occurrence in Indigenous Sabahan PRKN Parkinson’s Disease
Objective: To compare dyskinesia occurrence and associated factors in PRKN versus non-PRKN early-onset Parkinson's Disease (EOPD). Background: Biallelic pathogenic PRKN variants represent the commonest recessive…Towards the detection of troublesome dyskinesia in Parkinson’s disease using wearable sensors
Objective: To assess the feasibility of using movement energy heatmaps to detect troublesome dyskinesia in Parkinson’s disease (PD) during activities of daily living. Background: Recently,…SEMG for Dyskinesia Detection in Parkinson’s Disease Using Machine Learning
Objective: To evaluate whether surface electromyography (sEMG) signals from the biceps can detect dyskinesia in patients with Parkinson’s disease (PD) using machine-learning methods. Background: Levodopa-induced…Comparison Of Levodopa Dose Frequency And Parkinson’s Kinetigraph Metrics For Screening Advanced Parkinson’s Disease
Objective: 1. Evaluate how well levodopa dose frequency and Parkinson's Kinetigraph (PKG) metrics correspond with the 5-2-1 criteria for identifying Advanced Parkinson Disease (APD)2. Determine…Nutritional Status Assessment in Patients with Parkinson’s Disease
Objective: To evaluate the nutritional status of patients with Parkinson's disease (PD) and identify the clinical, psychosocial, and nutritional factors associated with it. Background: Malnutrition…Partial Duplication of NBEA in a Patient Presenting Chorea with Incomplete Penetrance
Objective: To report a novel genotype-phenotype correlation involving a partial duplication of the NBEA gene in a patient presenting with chorea. Background: NBEA has been identified as…Assessing Concordance Between Clinical judgment And 5-2-1 Criteria In Advanced Parkinsons Disease
Objective: 1. Assess how accurately clinicians diagnose Advanced Parkinson’s Disease (APD) in a routine clinical setting2. Evaluate concordance between 5-2-1 criteria and clinician judgement, including…From Cerebral Palsy to GNAO1-Related Movement Disorder: An Adult Diagnosis with Marked Response to Pallidal Deep Brain Stimulation
Objective: To report a case initially diagnosed as cerebral palsy, later identified as a GNAO1 gene–related movement disorder and to illustrate the therapeutic impact of…A Specific Neuronal Subpopulation in Globus Pallidus External Segment Mediates the Pathogenesis of Dyskinesia in Parkinson’s Disease
Objective: To clarify the causality between neuronal activity in globus pallidus external segment (GPe) and levodopa-induced dyskinesia (LID), and further ascertain the specificity of this…
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