Towards a method for accurate detection of diphasic dyskinesia
Objective: The present study aims to evaluate the efficacy of a body-worn sensor device to detect leg repetitive abnormal movements in patients with Parkinson's disease…Lack of depotentiation may not be a hallmark of Levodopa-induced dyskinesias
Objective: Paired associative stimumlation (PAS)-induced plasticity, a form of spike-time dependent plasticity (STDP), is deficient in PD. We tested whether (1) PAS-induced plasticity could be…High levodopa plasma concentration in the acute levodopa challenge test predicts levodopa-induced dyskinesia in Parkinson’s disease
Objective: We aimed to investigate the correlation between levodopa pharmacokinetics and levodopa-induced dyskinesia (LID) in Parkinson’s disease (PD). Background: In patients with PD, pulsatile dopaminergic…Adaptive vs Conventional deep brain stimulation for Parkinson’s disease: a eight-hours study
Objective: To compare the clinical efficacy of unilateral conventional DBS (cDBS) vs adaptive DBS (aDBS) based on local field potentials (LFP) delivered for 8 hours…Evaluation of Advanced Parkinson’s Patients Using Levodopa Carbidopa Instestinal Gel: Results of the Aegean Region of Turkey
Objective: The aim of the present study was to evaluate the outcome of LCIG treatment in advanced PD in Aegean Region of Turkey. Background: Levodopa/carbidopa…Sex-associated difference in the presentation and progression of Parkinson’s disease
Objective: Identifying the contribution of sex to the heterogeneity in presentation and progression of Parkinson’s disease (PD). Background: The different prevalence of Parkinson’s disease (PD)…Personal Kinetigraph and Deep Brain Stimulation with Parkinson’s Disease
Objective: To better understand the utility of a wearable wrist sensor in assessing and managing motor fluctuations in a population of patients with advanced Parkinson…Possible correlations between symptoms suggesting gastroparesis and dyskinesias in advanced Parkinson’s disease
Objective: The objective was to describe the spectrum of gastrointestinal complaints in a large cohort of patients with advanced Parkinson’s Disease (APD), who were repeatedly…Psychometric properties of clinical indicators of device-aided therapy eligibility among Parkinson’s disease patients: Real-world data from 6 countries
Objective: Evaluate the performance of clinical indicators for Device-aided Therapy (DAT) eligibility in real-world setting. Background: Timely initiation of appropriate DAT may improve quality of…Maladaptive motor cortex plasticity off medication in Parkinson’s disease patients with levodopa-induced dyskinesias
Objective: To test the hypothesis that motor cortex plasticity is maladaptive in Parkinson's disease (PD) patients suffering from dyskinesias, as compared to non-dyskinetic patients. Background:…
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