Managing severe dyskinesia in Parkinson’s Disease using 24-hour Levodopa/Carbidopa Intestinal Gel Infusion
Objective: We report the effective treatment of troublesome dyskinesias in Parkinson’s disease (PD), unresponsive to 16-hour daytime infusions, using 24-hour Levodopa/Carbidopa Intestinal Gel (LCIG). Background:…Differential Item Functioning in the Unified Dyskinesia Rating Scale (UDysRS)
Objective: Test if differential item functioning (DIF) due to gender, age, race/ethnicity or education level is present in UDysRS items. Background: Testing a rating…An Unusual Cause of Rhabdomyolysis in Parkinson’s disease
Objective: To describe an unusual cause of rhabdomyolysis in patient with advanced Parkinson’s disease (PD) treated with levodopa. Background: Rhabdomyolysis is a serious and life-threatening…Fibroblasts Implanted in Internal Pallidum of Parkinsonian Macaques Exert L-Dopa-Sparing Activity
Objective: To assess the effects of autologous implantation of fibroblasts in the internal globus pallidus of dyskinetic MPTP-lesioned monkeys upon motor behaviour and L-DOPA response.…Effect of levodopa-carbidopa intestinal gel on dyskinesia: Design of an open-label, randomized multicenter 12-week study in advanced Parkinson’s disease patients
Objective: To examine the effect of levodopa-carbidopa intestinal gel (LCIG, designated carbidopa-levodopa enteral suspension in the US) treatment relative to that of optimized medical treatment…Twelve-week sensor assessment in Parkinson’s disease: Impact on quality of life
Objective: To evaluate the effects of using wearables over a long time period on Health-Related Quality of Life (HRQoL) in Parkinson's disease (PD) patients. Background:…Synaptic homeostasis in Parkinson’s disease: An high-density EEG study in different stage of the disease
Objective: In order to corroborate these findings, we submitted 29 Parkinson's disease (PD) patients with different stage of disease to an all-night high-density EEG (hd-EEG)…Dyskinesias-reduced-self-awareness and theory of mind in Parkinson’s disease: A novel frame of interpretation
Objective: To analyze the existence of a relationship between Dyskinesias-reduced-self-awareness (DRSA) and abilities related to cognitive and affective Theory of Mind (ToM), which may represent…ADS-5102 (amantadine HCl) extended-release capsules reduced levodopa-induced dyskinesia in the phase 3 EASE LID study
Objective: To investigate the efficacy and safety of ADS-5102 (amantadine HCl) extended release capsules 340 mg daily at bedtime for the treatment of levodopa-induced dyskinesia…Validation of an electronic motor diary for patients with Parkinson’s disease
Objective: To determine the reliability and compliance to electronic motor diary in patients with PD. Background: Complexity of motor complications in Parkinson's disease (PD) makes…
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