A network imaging biomarker of X-linked dystonia-parkinsonism
Objective: To characterize a metabolic brain network associated with X-linked dystonia-parkinsonism (XDP). Background: X-linked dystonia-parkinsonism (XDP, DYT/PARK-TAF1, Lubag) is an X-linked recessive movement disorder characterized…Genetic spectrum of monogenic dystonia in Asian Indian patients
Objective: We aimed to identify potentially pathogenic genomic variations associated with dystonia in Asian Indian patients using whole exome sequencing. Background: Genomic variations associated with…The Pain in Dystonia Scale (PIDS): Development and Validation
Objective: To develop a new rating instrument for pain in AOID and validate it in the most common form of AOID, cervical dystonia (CD). Background:…A Phase 2, Double-blinded, Placebo-Controlled Trial to Evaluate the Efficacy and Safety of ABP-450 (PrabotulinumtoxinA) in Adults with Isolated Cervical Dystonia
Objective: To evaluate the safety and the efficacy of ABP-450 (prabotulinumtoxinA) in patients with cervical dystonia (CD). Background: ABP-450 (prabotulinumtoxinA) is a new 900kDA botulinumtoxinA.…Stop signal reaction time: A promising Diagnostic marker for Functional Cervical Dystonia
Objective: In the current study we explored the clinical utility of Stop Signal Reaction Time (SSRT) as a diagnostic marker for functional cervical dystonia (FCD).…Updates on the Outcomes of Botulinum Toxin Injections in Patients with Lower Limb Dystonia
Objective: To assess the therapeutic outcomes of botulinum toxin injections (BoNT) in patients with lower limb dystonia (LLD). Background: BoNT to the affected muscle groups…A Comparison of Cervical Dystonia in Parkinson’s Disease and Idiopathic Isolated Cervical Dystonia
Objective: To perform a prospective analysis of the prevalence and clinical characteristics of cervical dystonia in Parkinson’s disease (CD-PD) and compare these features to those…Clinical presentation and evolution of isolated focal and segmental dystonia in adults – 20 years experience from a botulinum toxin clinic
Objective: To provide unique data on the common patterns of muscles selected for injection and the time course of benefit and weakness for BoNT injections…Bilateral Globus Pallidus Internus Deep Brain Stimulation in Progressive Dystonia in Mohr-Tranebjaerg Syndrome: Case Report and Review
Objective: We report a MTS patient genetically confirmed who presented with progressive generalized dystonia, deafness, and cognitive and behavioral abnormalities that were treated by internal…Validating A New Writer’s Cramp Impairment Scale
Objective: A new writer’s cramp impairment scale (WCIS) was created and is compared with the existing writer’s cramp rating scale (WCRS). Background: Writer’s cramp (WC)…
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