MDS Abstracts

Abstracts from the International Congress of Parkinson’s and Movement Disorders.

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Articles tagged "Dystonia: Pathophysiology"

  • 2025 International Congress

    The Effect of Body Position on Cortical and Peripheral Neurophysiology of Adductor-type Laryngeal Dystonia: A Pilot Study

    J. Pierce, R. Gillam, B. Kirwan, A. Dorval, A. Hancock, A. Stark, D. Legler, H. da Silva, M. Smith, K. Simonyan, J. Barkmeier-Kraemer (Salt Lake City, USA)

    Objective: To compare the effect of body position on CNS and PNS function and associated adductor-type laryngeal dystonia (AdLD) voice symptomatology. Background: Body position impacts…
  • 2025 International Congress

    Tracking Physiological Biomarker Activity in the Globus Pallidus Internus in Two Dystonia Patients Implanted with Medtronic Percept™

    S. Alberico, M. Berns, B. Pereira Rios, J. Aman, M. Park, D. Darrow, J. Vitek, L. Almeida (Minneapolis, USA)

    Objective: Explore potential biomarkers in dystonia patients implanted with Medtronic Percept™. Background: Though highly variable in presentation and underlying cause, individuals with dystonia present with…
  • 2025 International Congress

    White Matter and Subcortical Alterations in Focal Dystonia: A MRI Study of Subtype-Specific Brain Changes

    J. de Paiva, D. de Faria, V. Borges, S. Silva, H. de Ferraz, P. Aguiar (Sao Paulo, Brazil)

    Objective: To assess structural brain alterations in patients with cervical dystonia (CD) and focal upper limb dystonia (ULD) relative to healthy controls, using MRI exploratory…
  • 2025 International Congress

    White matter alterations in Yeo’s motor network correlate with kinematic writing behavior in writer’s cramp dystonia

    A. Murlikrishnan, B. Dahlben, M. Lutz, S. Davis, C. Mcintyre, N. Bukhari-Parlakturk (Durham, USA)

    Objective: To investigate the relationship between white matter changes in the motor network and kinematic writing measures in WC and healthy volunteers (HV). Background: Writer’s…
  • 2025 International Congress

    Central Neuromodulatory Effects of Sodium Oxybate in Laryngeal Dystonia: A Pharmacological fMRI Study

    L. O'Flynn, A. Hamzehei Sichani, A. Worthley, N. Sharma, P. Song, K. Simonyan (Boston, USA)

    Objective: To examine the central effects of sodium oxybate in patients with alcohol-responsive (EtOH+) laryngeal dystonia (LD). Background: LD is a task-specific form of isolated…
  • 2025 International Congress

    Multimodal Neurophysiological Evaluation in Patients with Different Dystonia Subtypes

    T. Grippe, N. Sheth, A. Bhattacharya, JC. Chen, N. Raies, H. Taskin, N. Naeini, R. Annirood, JF. Nankoo, J. Baarbe, R. Chen (Toronto, Canada)

    Objective: Evaluate dystonia patients with different subtypes using a standardized neurophysiological test battery. Background: Dystonia pathophysiology is characterized by circuit dysfunction involving the thalamus, basal…
  • 2025 International Congress

    Clinical Improvement after Deep Brain Stimulation is associated with the Suppression of Pallidal low-frequency Oscillations in Patients with Dystonia

    C. Palmisano, J. Del Vecchio, I. Hanafi, A. Al Habbal, C. Matthies, G. Pezzoli, J. Volkmann, P. Capetian, N. Pozzi, S. Haufe, I. Isaias (Wuerzburg, Germany)

    Objective: to investigate the relationship between pallidal activity and clinical response to deep brain stimulation (DBS) of the globus pallidus internus (GPi) Background: GPi-DBS is…
  • 2025 International Congress

    Focal Lower Limb Myoclonus Heralding Adult Onset Fulminant SSPE

    S. Jha, S. Pendyala (Kolkata, India)

    Objective: We report a case adult onset fulminant SSPE with focal lower limb myoclonus as the predominant presenting movement disorder. Background: Myoclonus remains a defining…
  • 2025 International Congress

    Status Dystonicus is a Distinct State Characterized by Pallidal Beta-band Activity

    A. Balachandar, L. Vogt, K. Mithani, S. Coleman, M. Ebden, A. Leblanc-Miller, S. Breitbart, A. Fasano, C. Gorodetsky, G. Ibrahim (Toronto, Canada)

    Objective: To identify distinct pallidal local field potential (LFP) signatures characterizing status dystonicus (SD) from non-SD dystonia. Background: SD is a poorly understood neurological emergency…
  • 2025 International Congress

    GPi Stimulation shows Immediate Effects in Motor Improvement within Pediatric Patients with Movement Disorders

    A. Brucker, A. Zakharova, S. Seyyed Mousavi, A. Salisbury, J. Olaya, M. Liker, T. Sanger (Orange, USA)

    Objective: This study was conducted in order to determine whether GPi stimulation has immediate clinical effect in patients with dystonia who underwent Deep Brain Stimulation…
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