Multimodal Neurophysiological Evaluation in Patients with Different Dystonia Subtypes
Objective: Evaluate dystonia patients with different subtypes using a standardized neurophysiological test battery. Background: Dystonia pathophysiology is characterized by circuit dysfunction involving the thalamus, basal…Clinical Improvement after Deep Brain Stimulation is associated with the Suppression of Pallidal low-frequency Oscillations in Patients with Dystonia
Objective: to investigate the relationship between pallidal activity and clinical response to deep brain stimulation (DBS) of the globus pallidus internus (GPi) Background: GPi-DBS is…Focal Lower Limb Myoclonus Heralding Adult Onset Fulminant SSPE
Objective: We report a case adult onset fulminant SSPE with focal lower limb myoclonus as the predominant presenting movement disorder. Background: Myoclonus remains a defining…Status Dystonicus is a Distinct State Characterized by Pallidal Beta-band Activity
Objective: To identify distinct pallidal local field potential (LFP) signatures characterizing status dystonicus (SD) from non-SD dystonia. Background: SD is a poorly understood neurological emergency…GPi Stimulation shows Immediate Effects in Motor Improvement within Pediatric Patients with Movement Disorders
Objective: This study was conducted in order to determine whether GPi stimulation has immediate clinical effect in patients with dystonia who underwent Deep Brain Stimulation…Cerebellar connectivity predicts early response to GPi-DBS in dystonia.
Objective: To investigate the structural and functional connectivity of patients who respond early after deep brain stimulation (DBS) for dystonia. Background: DBS is an effective…Probing Social Cognition and Emotional Facial Expression Recognition in Cervical Dystonia through Integration of EEG and Eye-Tracking
Objective: To examine facial emotional recognition and processing in Cervical Dystonia (CD) subjects as a test of whether Social Cognition (SoC) is impaired compared to…Molecular Studies Reveal Overactive Interferon (IFN) Pathway in Two Monogenic Inherited Dystonia Types.
Objective: Our overall objective was to investigate the involvement of type I interferons (IFNs) in DYT-PRKRAand DYT-EIF2AK2. IFNs are antiviral cytokines produced by all cell…Perceptual Decision Making in Cervical Dystonia: Development of a a Novel Integrated Neurobehavioural-Neurophysiological Method.
Objective: To investigate perceptual decision-making (PDM) in cervical dystonia (CD) using a novel paradigm and determine the neural basis of PDM abnormalities in a CD…The Cholinergic System in Cervical Dystonia – An [18F]-FEOBV PET study
Objective: To investigate presynaptic cholinergic functioning in cervical dystonia (CD) by comparing [18F]-FEOBV binding in patients and controls, as well as exploring correlations with motor…
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