Precision Functional MRI Mapping of Therapeutic Response in Focal Hand Dystonia
Objective: To apply precision functional mapping (PFM) to characterize individual-specific network changes in persons with focal hand dystonia (FHD) before and after botulinum toxin (BTX)…Excitatory/inhibitory Balance Differences Suggests Distinct Pathophysiology Between Blepharospasm and Cervical Dystonia
Objective: To determine if excitatory/inhibitory balance (E/I) within the sensorimotor network is linked to motor symptoms in two distinct subtypes of isolated focal dystonia. Background:…Action-Induced Dystonic Opisthotonus as an Atypical Presentation in Ataxia Telangiectasia
Objective: We present a rare case of Ataxia-telangiectasia (AT) characterized by intermittent action-induced dystonic opisthotonus causing frequent vomiting after meals intake [figure1]. Background: AT is…The Effect of Body Position on Cortical and Peripheral Neurophysiology of Adductor-type Laryngeal Dystonia: A Pilot Study
Objective: To compare the effect of body position on CNS and PNS function and associated adductor-type laryngeal dystonia (AdLD) voice symptomatology. Background: Body position impacts…Tracking Physiological Biomarker Activity in the Globus Pallidus Internus in Two Dystonia Patients Implanted with Medtronic Percept™
Objective: Explore potential biomarkers in dystonia patients implanted with Medtronic Percept™. Background: Though highly variable in presentation and underlying cause, individuals with dystonia present with…White Matter and Subcortical Alterations in Focal Dystonia: A MRI Study of Subtype-Specific Brain Changes
Objective: To assess structural brain alterations in patients with cervical dystonia (CD) and focal upper limb dystonia (ULD) relative to healthy controls, using MRI exploratory…White matter alterations in Yeo’s motor network correlate with kinematic writing behavior in writer’s cramp dystonia
Objective: To investigate the relationship between white matter changes in the motor network and kinematic writing measures in WC and healthy volunteers (HV). Background: Writer’s…Central Neuromodulatory Effects of Sodium Oxybate in Laryngeal Dystonia: A Pharmacological fMRI Study
Objective: To examine the central effects of sodium oxybate in patients with alcohol-responsive (EtOH+) laryngeal dystonia (LD). Background: LD is a task-specific form of isolated…Multimodal Neurophysiological Evaluation in Patients with Different Dystonia Subtypes
Objective: Evaluate dystonia patients with different subtypes using a standardized neurophysiological test battery. Background: Dystonia pathophysiology is characterized by circuit dysfunction involving the thalamus, basal…Clinical Improvement after Deep Brain Stimulation is associated with the Suppression of Pallidal low-frequency Oscillations in Patients with Dystonia
Objective: to investigate the relationship between pallidal activity and clinical response to deep brain stimulation (DBS) of the globus pallidus internus (GPi) Background: GPi-DBS is…
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