Neuronal responses of pallidal and cerebellar receiving thalamic nuclei to neck exertion in cervical dystonia patients
Objective: The goal of the study was to find differences in spontaneous and neck-related activity of pallidal and cerebellar receiving thalamic nuclei in patients with…Start React Paradigm In Patients With Cervical Dystonia
Objective: Compare StartReact paradigm in cervical dystonia (CD) patients compared to matched healthy participants. Background: The voluntary response to vestibular stimulation is enhanced in CD…Abnormal cerebellar learning in cervical dystonia
Objective: This study was conceptualized to asses if patients with cervical dystonia (CD) exhibit deficits in cerebellar function tested by motor adaptation and motor sequence…Peripheral trauma elicits a dystonic phenotype in a DYT1 transgenic mouse model
Objective: To induce a dystonic phenotype in DYT1 (hΔGAG3) mice through peripheral trauma in order to analyze metabolic and structural alterations in the striatum. Background:…Disease Modeling of Lesch-Nyhan Disease Using Induced Pluripotent Stem Cells
Objective: To create a resource of induced pluripotent stem cells (iPSCs) as models for exploring mechanisms of pathogenesis in Lesch-Nyhan disease (LND). Background: LND is…Striatum of the ouabain-induced pharmacological DYT12 mouse model is affected by structural and metabolic abnormalities
Objective: To study changes in neuronal morphology and neurotransmitter metabolism in the striatum of a pharmacological DYT12 mouse model after induction of a dystonic phenotype…Neuropathology of dopa-responsive dystonia due to Tyrosine hydroxylase deficiency
Objective: To describe detailed neuropathology findings from an autopsy case of dopa-responsive dystonia (DRD) with genetically confirmed tyrosine hydroxylase deficiency (THD). Background: DRD comprises a…Asymmetry of pallidal neuronal activity correlates with head rotation in patients with cervical dystonia
Objective: To find correlation between single unit activity in globus pallidus (GP) and neck turning in patients with cervical dystonia (CD). Background: Asymmetric GP local…Multivariate analysis of writer`s cramp: a study with advanced multi-channel microelectrode recording system
Objective: To quantify difference in WC patients with Concordant mirror movements(MMs) from those with Discordant MMs. Background: Invasive methods are encouragive for quantitative analysis. The…Abnormal patterns of action selection in the dominant motor cortex in writer’s cramp
Objective: To test if (1) abnormal right dorsal premotor cortex (dPMC) to left primary motor cortex (M1) interaction during writing with right hand contributes to…
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