Proof-of-Principle Quantitative EEG Study of CX-8998, an Oral, Potent and Selective T-Type Calcium antagonist in development for symptomatic treatment of Essential Tremor and Parkinson’s disease Tremor
Objective: To study the pharmacodynamics (PD) of CX-8998, using pharmaco-electroencephalography (phEEG) and define plasma concentrations of CX-8998 which are pharmacologically active on objective CNS parameters.…The utility of electrophysiological tests in the differentiation of upper limb tremor in young-onset patients
Objective: To explore the diagnostic utility of neurophysiologic tests in young-onset patients who present primarily with upper limb action tremor. Background: In young-onset patients, isolated…Magnetic resonance-guided focused ultrasound unilateral thalamotomy for the treatment of essential tremor: Outcomes and complications after 1 year of follow-up in 21 patients
Objective: To report the clinical experience in our center (CINAC-HM Puerta del Sur) in the treatment of essential tremor (ET) with Magnetic Resonance guided Focused…Education in hyperkinetic movement disorders in Cameroonian health providers
Objective: To evaluate the educational gaps in hyperkinetic movement disorders among a widely-varied sample of Cameroonian health providers and improve understanding through a practical training…Cognitive impairment and neuropsychological disorders in essential tremor
Objective: Our research aims to investigate the characteristic of non-motor symptoms of essential tremor patients, particularly cognition and anxiety depression degree. Background: Non-motor symptoms of…The effect of thalamic and subthalamic deep brain stimulation on speech in patients with essential tremor: A prospective, randomized, double-blind crossover study
Objective: To investigate the effect of thalamic (ventral intermediate nucleus, VIM) and subthalamic (posterior subthalamic area, PSA) deep brain stimulation (DBS) in patients with essential…Resting-state fMRI study on drug-naive essential tremor patients with head tremor
Objective: This study used resting-state fMRI to evaluate intrinsic brain activity in drug-naive patients with essential tremor with and without head tremor. Background: Head tremor…Thalamic Tremor Following Focused Ultrasound Thalamotomy for Essential Tremor
Objective: To describe a case of dystonic tremor developing after Magnetic Resonance Guided Focused Ultrasound Thalamotomy (MRgFUS) in a patient with essential tremor (ET). Background:…A functional micro-electrode mapping of ventral thalamus in Essential Tremor
Objective: Understanding the pathomechanisms of Essential Tremor (ET) with higher spatial and temporal precision is of important clinical relevance. While the efficiency of Deep Brain…Identifying therapeutic targets from spontaneous beneficial brain lesions
Objective: To determine whether rare cases in which spontaneously occurring brain lesions improved tremor can be used to identify a therapeutic target. Background: The search…
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