MDS Abstracts

Abstracts from the International Congress of Parkinson’s and Movement Disorders.

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Articles tagged "Eye movement"

  • 2025 International Congress

    Eye tracking identifies biomarkers predicting Parkinson’s disease before motor symptom onset

    A. Yoritaka, M. Ando, S. Nakayama, K. Fusegi, S. Nojiri, A. Tozuka, Y. Wang, W. Urasaki, N. Hattori (Saitama, Japan)

    Objective: To investigate eye movement changes as an early motor biomarker of Parkinson’s disease (PD) in patients with REM sleep behavior disorder (RBD). Background: RBD…
  • 2025 International Congress

    Resolution Dependence of Machine Learning for Differential Diagnosis of Parkinsonian Eye Movements

    O. Bredemeyer, S. Patel, J. Fitzgerald, C. Antoniades (Oxford, United Kingdom)

    Objective: To establish the extent to which high temporal resolution is required to differentiate between parkinsonian disease states from eye movements. Background: Previous studies have…
  • 2025 International Congress

    Digital measurement of ocular microtremor in Parkinson’s Disease: Analytical and clinical validation

    L. Graham, R. Vitorio, P. Tait, R. Walker, A. Godfrey, R. Morris, S. Stuart (Newcastle-upon-Tyne, United Kingdom)

    Objective: This pilot study examined the analytical and clinical validation of OMT measurement via the iTremor ONE device in PwPD. Background: Ocular microtremor (OMT) is…
  • 2025 International Congress

    Machine Learning Model using Eye Movements for the Differential Diagnosis of iPD and Atypical Parkinsonian Syndromes

    A. Sekar, D. Kaski (London, United Kingdom)

    Objective: To develop a machine learning (ML) model to first between differentiate between healthy controls, idiopathic PD, Atypical Parkinsonian syndromes and then further subclassify as…
  • 2025 International Congress

    Oculomotor Differences in PARK2 PD: a Study of Structured and Unstructured Eye Movements in an Irish Genetic Cohort

    A. Gallagher, C. O'Keeffe, J. Inocentes, M. Bradley, E. Donlon, B. Coe, B. White, R. Walsh, T. Lynch, R. Reilly, D. Munoz, C. Fearon (Dublin, Ireland)

    Objective: To identify and measure how eye movements differ between biallelic PARK2 carriers, carriers of a single PARK2 variant and non-carriers using structured and unstructured…
  • 2025 International Congress

    Concomitant Progressive Supranuclear Palsy and Amyotrophic Lateral Sclerosis Versus Motoneuron Phenotype of PSP in Ukrainian Patient

    Y. Trufanov, Y. Compta, M. Trishchynska, N. Khanenko, G. Chupryna, V. Sereda, A. Ovchynnykova (Kyiv, Ukraine)

    Objective: To provide a description of a rare case of mixed progressive supranuclear palsy (PSP) and amyotrophic lateral sclerosis (ALS) in Ukrainian patient. Background: The…
  • 2025 International Congress

    Multiscale entropy: a New Oculomotor Measure of PSP.

    C. O'Keeffe, A. Gallagher, J. Inocentes, B. Coe, B. White, D. Brien, D. Munoz, R. Walsh, T. Lynch, C. Fearon (Dublin, Ireland)

    Objective: The objective of this study was investigate whether multiscale entropy, a measure of complexity, when applied to the path of unconstrained eye movements could…
  • 2025 International Congress

    Utilizing the 15-item modification of the PSPRS rating scale (mPSPRS-15) as the primary endpoint for future clinical trials in progressive supranuclear palsy

    F. Nery, T. Nevmyrych, J. Murphy, S. Wu, Y. Zabar, A. Gafson, S. Bullain, J. O’Gorman (Cambridge, USA)

    Objective: To compare the properties of PSPRS-28, mPSPRS-15, and the rPSPRS-10 and assess their utility as a primary endpoint in PSP trials. Background: Progressive supranuclear…
  • 2025 International Congress

    Peripheral neuropathy in Autosomal Recessive Spinocerebellar Ataxia due to ANO10 mutation – Expanding the phenotypic spectrum

    A. Vijayaraghavan (Thiruvananthapuram, India)

    Objective: SCAR10/ Adult-onset autosomal recessive cerebellar ataxia is an exceptionally rare form of ataxia, caused by mutations in the ANO10 gene and the specific genotype–phenotypecorrelation…
  • 2025 International Congress

    Oculomotor Abnormalities in Spinocerebellar Ataxia Type-12: A Functional Neuroimaging Study

    P. Pankaj, A. Srivastava, S. Kumaran, A. Garg, R. Agarwal, M. Kumar, A. Sonakar, A. Nehra (New Delhi, India)

    Objective: This study aimed to investigate eye movements, specifically dysmetric saccades and cerebellar nystagmus, in Spinocerebellar Ataxia Type-12 (SCA12) using functional magnetic resonance imaging (fMRI)…
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