The Sedentary Index (SI) for Daily Life Activity Monitoring in Progressive Supranuclear Palsy (PSP)
Objective: To confirm the feasibility of daily life physical activity monitoring in PSP using a single activPAL sensor, and to examine preliminary associations between overall…Harnessing Digital Biomarkers to Monitor Early Parkinson’s Disease Progression
Objective: This study aimed to identify gait metrics capable of capturing disease progression in individuals with early Parkinson’s disease (PD). Background: Digital gait assessments have…Center of Mass and Center of Pressure interactions during Gait in people with Parkinson’s Disease
Objective: To compare lateral stability during gait in people with Parkinson’s Disease (PD), compared to healthy controls (HC). Background: PD is a progressive neurodegenerative disorder[1],…Clustering and Identification of Parkinson’s Disease Severity Subtypes Using Multimodal Data and Machine Learning Approaches
Objective: This study aimed to classify Parkinson’s disease (PD) severity subtypes by integrating objective multimodal data with machine learning (ML) techniques. We applied unsupervised clustering…The Radiographic Overlap Between Normal Pressure Hydrocephalus (NPH) and Progressive Supranuclear Palsy (PSP): When Looks Can Be Deceiving
Objective: To demonstrate the overlap on radiographic metrics between NPH and PSP. Background: The neuroradiological hallmark of NPH is non-obstructive ventriculomegaly (Evans’ index (EI) >0.3).…Trihexyphenidyl as a Treatment for Severe Freezing of Gait in Parkinson’s Disease: A Case Report
Objective: To present a unique case in which trihexyphenidyl was used as an effective treatment to dramatically reduce freezing of gait (FoG) in a Parkinson’s…Perceived Versus Actual Performance During Dual-Task Walking: Insights from Parkinson’s Disease
Objective: To explore the concordance between perceived difficulty and focus, to actual performance during a dual-task (DT) two-minute walk test (2MWT) in people with Parkinson’s…Application of Multi-Camera Videography for Detecting PD-related Gait Deficiencies
Objective: To identify and measure PD-specific gait signals in multi-camera videos for differentiating PD vs control (non-PD), without using specialized equipment (e.g., motion capture). Background:…The Severity and Burden of Movement Disorder Symptomology in Patients with Cerebrotendinous Xanthomatosis: A US-based Survey
Objective: To provide information about the presentation, burden, and severity of movement disorder (MD) symptoms in cerebrotendinous xanthomatosis (CTX) from the patient perspective. Background: CTX…Continuous Subcutaneous Dopaminergic Stimulation: Exploring the impact of Foslevodopa/Foscarbidopa on Gait in Parkinson’s disease.
Objective: The primary objective of this study is to investigate the effect of continuous subcutaneous infusion (CSCI) of foslevodopa/foscarbidopa (FL/FC) on gait in those with…
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