Finding an optimal lead trajectory for a better stimulated volume in movement disorder therapy
Objective: Defining the best lead trajectory (Arc; Ring) with a computational 3D stereotactic model of the Globus Pallidus internus (GPi) and investigating the influence of…Results from a double-blind trial of pallidal DBS for Tourette’s syndrome: Are there any predictors of surgery outcome?
Objective: To explore whether individual patient characteristics can indicate response to treatment in a trial of bilateral globus pallidus internus (GPi) deep brain stimulation (DBS)…DBS targeting: Validation of 3T MR image guided targeting using post-mortem 17T MR microscopy
Objective: This work helps validate the utility of direct targeting using 3T T1 inverted sequences with atlas application during planning for DBS electrode placement. We…When DBS can be of benefit in Huntington’s disease
Objective: To report on a patient with HD and disabling truncal dystonia who was treated with bilateral GPi DBS. Background: HD is an autosomal-dominant disorder…Sweet spot of antidystonic effect in pallidal neurostimulation
Objective: We investigated Volumes of Neural Activation (VNAs) in dystonia subjects under effective bilateral pallidum deep brain stimulation (DBS). We aimed to disentangle the sweet…Fahr’s syndrome in a Filipino female with hearing loss and polycystic ovaries: A case report
Objective: The objective of this case report is to document a case of Fahr's syndrome including its varied clinical manifestations. Background: Idiopathic basal ganglia calcification,…Single unit activity of globus pallidus during voluntary movements in patients with cervical dystonia
Objective: To reveal the electrophysiological mechanism of voluntary movements with and without neck muscle exertion in patients with cervical dystonia. Background: Globus pallidus, as part…Refined basal ganglia model accounting for GPi modulation of thalamic tonic and burst modes
Objective: To test our hypothesis that a principal role of GPi GABAergic output is to regulate the dual burst and tonic modes of thalamocortical neurons.…Recent result of indicative evaluation for deep brain stimulation of Parkinson’s disease patients
Objective: To report recent result of indicative evaluation for deep brain stimulation (DBS) of Parkinson's disease (PD) patients, ant to investigate relationship between pathological condition…Impulsive action tendencies in GPi DBS Parkinson’s patients
Objective: To test the effects of GPi DBS on susceptibility to impulsive action errors and the proficiency of reactive inhibitory control to counteract interference from…
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