The effect of levodopa on speech in advanced Parkinson’s Disease: acoustic analysis and correlation with motor features and dyskinesia
Objective: Analyse the effects of levodopa on speech and its possible relationship with motor features and dyskinesias in a group of advanced Parkinson’s disease (PD)…High cost of medications for Parkinson’s Disease patients in a rural population of Gujarat, India
Objective: To understand the economic burden of the cost of Parkinson’s Disease (PD) medications for outpatients receiving care at Shree Krishna Hospital (SKH) in Karamsad,…Levodopa Effects on Visuospatial Working Memory in Parkinson’s Disease
Objective: To investigate the effects of levodopa on memory load and distractor resistance during visuospatial working memory (WM) in Parkinson’s disease (PD). Background: Visuospatial WM…Laboratory Performance of the DopaFuse® Delivery System
Objective: SynAgile has developed the DopaFuse Delivery System to noninvasively and continuously administer levodopa/carbidopa (LD/CD) into the mouths of patients with Parkinson’s Disease (PD). The…Preclinical Development of a Novel Carbidopa/Levodopa Precision Olfactory Delivery (POD®) Drug-Device Combination Product for the Treatment of OFF Episodes in Parkinson’s Disease
Objective: This series of preclinical studies of novel levodopa and carbidopa/levodopa powder formulations delivered by the POD device to rats and non-human primates (NHP) guided…Study on the effect of levodopa administration on serum zinc levels in Parkinson’s disease patients
Objective: Since zinc-chelating action of levodopa has been reported in the past, we measured serum zinc level in patients with Parkinson's disease (PD) at our…Liquid Levodopa/Carbidopa – An underutilized, cost effective treatment of advanced Parkinson’s disease in the developing world
Objective: Advanced Parkinson’s disease manifests with “on-off” phenomenon, dyskinesias and increasing symptom severity . Managing it in developing countries is difficult given the low per…Impaired fonction of mirror neurons and the role of levodopa in PD patients
Objective: Study of the emotional mirroring and its modulation by levodopa treatment in fluctuating PD patients with no significant cognitive burden as assessed by regular…Dopamine receptor variants alter outcomes with levodopa in early-stage Parkinson’s disease
Objective: To examine if specific single nucleotide polymorphisms (SNPs) in the genes for dopamine receptors 2 and 3 (DRD2, DRD3) correlate with worse outcomes within specific…Impact of ND0612 on patient reported outcomes: A blinded rater study of 2 dosing regimens
Objective: Primary analyses of this Phase 2 study have demonstrated significant efficacy of ND0612 in reducing OFF time and improving motor status. This secondary analysis…
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