MDS Abstracts

Abstracts from the International Congress of Parkinson’s and Movement Disorders.

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Articles tagged "Locomotion"

  • 2016 International Congress

    Twelve-week sensor assessment in Parkinson’s disease: Impact on quality of life

    J.M.T. Van Uem, K.S. Maier, A.T. Santos, O. Fagerbakke, F. Larsen, J.J. Ferreira, W. Maetzler (Tübingen, Germany)

    Objective: To evaluate the effects of using wearables over a long time period on Health-Related Quality of Life (HRQoL) in Parkinson's disease (PD) patients. Background:…
  • 2016 International Congress

    Therapeutic protocol for Parkinson’s patient with freezing based on action observation plus sonification: Preliminary results

    S. Mezzarobba, M. Grassi, M. Catalan, L. Pellegrini, R. Valentini, B. Krüger, P. Manganotti, P. Bernardis (Trieste, Italy)

    Objective: To evaluate the effects of a novel experimental protocol to treat patients with Parkinson's disease (PwP) and freezing of gait (FoG), using functional, and…
  • 2016 International Congress

    Quantification of postural stability in Parkinson’s disease patients utilizing mobile technology

    J.L. Alberts, M.M. Koop, S.M. Linder, T. Dey, S.J. Ozinga (Cleveland, OH, USA)

    Objective: To validate the use of a mobile device and an associated biomechanical outcome to objectively quantify postural stability in Parkinson's disease (PD) patients. Background:…
  • 2016 International Congress

    A novel C. elegans model for identification of small molecules that target alpha-synuclein-mediated toxicity

    L.V. Kalia, K. Menezes, Y. Zhang, S. Ishikura, N. Tran, H. Chau, A.M. Lozano, S.K. Kalia, J.G. Culotti, S. Suo, W.S. Ryu (Toronto, ON, Canada)

    Objective: To develop a novel transgenic C. elegans model to study dopaminergic neurodegeneration mediated by alpha-synuclein. Background: Targeting alpha-synuclein could be a disease-modifying strategy for…
  • 2016 International Congress

    Neural mechanisms underlying step initiation failure in patients with Parkinson’s disease and freezing of gait

    M. Gilat, M. Georgiades, J.M. Shine, K.A. Ehgoetz Martens, C.C. Walton, J.M. Hall, S.J.G. Lewis (Sydney, Australia)

    Objective: To investigate the neural mechanisms underlying gait initiation failure in Parkinson's disease patients with Freezing of Gait. Background: Freezing of Gait (FOG) is a…
  • 2016 International Congress

    Modulation of local field potentials during gait in the STN of patients with Parkinson’s disease

    F. Hell, J.H. Mehrkens, A. Plate, K. Bötzel (München, Germany)

    Objective: PD patients with implanted DBS electrodes allow for the investigation of basal ganglia activity during gait. Background: Whereas the overall spectral content of local…
  • 2016 International Congress

    Optogenetic silencing of locus coeruleus activity in mice impairs cognitive flexibility in an attentional set-shifting task

    K. Janitzky, M. Lippert, A. Engelhorn, J. Tegtmeier, J. Goldschmidt, H.J. Heinze, F.W. Ohl (Magdeburg, Germany)

    Objective: In this study we used unilateral optogenetic silencing of the LC in an attentional set-shifting task (ASST) to evaluate the influence of the LC…
  • 2016 International Congress

    The interactive walkway: Towards assessing gait-environment interactions in a clinical setting

    D.J. Geerse, M. Roerdink, B. Coolen, J. Marinus, J.J. van Hilten (Leiden, Netherlands)

    Objective: To determine the usability of the Interactive Walkway (IWW) for the assessment of walking adaptability. Background: A prerequisite for safe walking is one's ability…
  • 2016 International Congress

    A step forward to the future: UPDRS kinematic measures for telemedicine

    G. Albani, C. Azzaro, F. Parisi, C. Ferraris, M. Giuberti, L. Contin, D. Pianu, L. Pradotto, V. Cimolin, N. Cau, M. Galli, R. Nerino, G. Ferrari, A. Mauro (Piancavallo, Italy)

    Objective: We set up an experimental instrumentation to quantify selected items of UPDRS by a Kinect technology and body sensory-network (BSN), destinated to an easy…
  • 2016 International Congress

    A rapid chemical-genetic screen utilising impaired movement phenotypes in caenorhabditis elegans

    K. Schmeisser, Y.F. Ghassemi, C. Maios, A. Parker (Montreal, QC, Canada)

    Objective: Development of a fast and unbiased screening method to identify C. elegans mutants with movement disabilities and drugs to improve impaired locomotion. Background: Identifying…
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