A combined cognitive and motor exercise program for people with Parkinson’s disease and Freezing of gait; a pilot study.
Objective: The purpose of this pilot study was to explore whether this combined cognitive and motor exercise program would 1) improve freezing of gait (FOG)…A novel C. elegans model for identification of small molecules that target alpha-synuclein-mediated toxicity
Objective: To develop a novel transgenic C. elegans model to study dopaminergic neurodegeneration mediated by alpha-synuclein. Background: Targeting alpha-synuclein could be a disease-modifying strategy for…Neural mechanisms underlying step initiation failure in patients with Parkinson’s disease and freezing of gait
Objective: To investigate the neural mechanisms underlying gait initiation failure in Parkinson's disease patients with Freezing of Gait. Background: Freezing of Gait (FOG) is a…Modulation of local field potentials during gait in the STN of patients with Parkinson’s disease
Objective: PD patients with implanted DBS electrodes allow for the investigation of basal ganglia activity during gait. Background: Whereas the overall spectral content of local…Optogenetic silencing of locus coeruleus activity in mice impairs cognitive flexibility in an attentional set-shifting task
Objective: In this study we used unilateral optogenetic silencing of the LC in an attentional set-shifting task (ASST) to evaluate the influence of the LC…The interactive walkway: Towards assessing gait-environment interactions in a clinical setting
Objective: To determine the usability of the Interactive Walkway (IWW) for the assessment of walking adaptability. Background: A prerequisite for safe walking is one's ability…A step forward to the future: UPDRS kinematic measures for telemedicine
Objective: We set up an experimental instrumentation to quantify selected items of UPDRS by a Kinect technology and body sensory-network (BSN), destinated to an easy…A rapid chemical-genetic screen utilising impaired movement phenotypes in caenorhabditis elegans
Objective: Development of a fast and unbiased screening method to identify C. elegans mutants with movement disabilities and drugs to improve impaired locomotion. Background: Identifying…Effects of videogame step training on gait adaptability in people with Parkinson´s disease – A randomized controlled trial
Objective: To evaluate the effect of home-based interactive videogame step training on gait adaptability performance in people with Parkinson's disease (PD). Background: The ability to…Virtual rehabilitation: A therapy for parkinsonism?
Objective: To determine the effectiveness of vestibular rehabilitation exercises that use virtual reality technology through pre and post application of the Berg Balance Scale (BBS),…
