Clinical And Cerebellar Structural Alterations In Parkinson’s Disease Patients With Freezing Of Gait
Objective: To assess clinical and cerebellar volume differences in Parkinson’s disease (PD) patients with and without freezing of gait (PD-FoG and PD-NOFoG). Background: Cerebellum plays…Atrophy In Multiple System Atrophy Relates To Mitochondrial And Oligodendrocytic Processes
Objective: To investigate the gene expression and neurobiological underpinnings of brain atrophy in MSA using imaging transcriptomics and PET-based molecular annotation Background: The biological mechanisms…Widespread White Matter Changes in Manifest Huntington’s Disease
Objective: To characterize white matter changes in Huntington’s Disease (HD). Background: HD is a genetic neurodegenerative disorder characterized by motor, cognitive, and psychiatric symptoms. Diffusion Tensor…χ-DBS: An Open-Source Susceptibility Atlas Tool for Deep Brain Stimulation Target Visualization and Segmentation
Objective: This work is motivated by the need for atlas creation tools for susceptibility maps presurgically acquired for deep brain stimulation (DBS). Segmentations aid in…Diffusion MRI Changes Linked to α-Synuclein Seed Amplification Status in Parkinson’s Disease
Objective: To compare free-water (FW) imaging in individuals with Parkinson’s disease (PD), with positive vs. negative cerebrospinal fluid (CSF) α-synuclein seed amplification assay (SAA) status.…White Matter Abnormalities in Progressive Supranuclear Palsy (PSP) vs. Parkinson’s Disease (PD): Evaluation with a Convolutional Neural Network (CNN)-Based Tool
Objective: This study aimed to compare white matter hyperintensity (WMH) burden between PSP and PD using a novel AI-based tool for more accurate WMH volume…Correlation of 7T MRI Susceptibility and Retinal Nerve Fiber Thickness with Neurological Severity in Wilson’s Disease
Objective: To evaluate susceptibility changes in the lentiform nucleus using 7T MRI and peripapillary retinal nerve fiber layer (p-RNFL) thickness using Optical Coherence Tomography (OCT)…Brain Energetics: Changes in Healthy Aging and Parkinson’s Disease
Objective: To identify in vivo bioenergetic alterations in healthy aging and Parkinson’s disease (PD). Background: PD-related cerebral metabolic alterations have been robustly characterized [1] and…Clinical and neuro-imaging predictors of falls in PLA2G6-related Parkinsonism: a retrospective study
Objective: This study investigates clinical and neuroimaging predictors of recurrent falls and gait disturbances in PLA2G6-related Parkinsonism. Background: PLA2G6-related Parkinsonism is characterized by dystonia-parkinsonism, cerebellar…Association between Imaging Glymphatic Dysfunction Markers and Clinical Symptoms in Progressive Supranuclear Palsy
Objective: This study aims to explore possible glymphatic dysfunction using diffusion tensor image analysis along the perivascular space (DTI-ALPS) in patients with progressive supranuclear palsy…
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