Plasma p-tau217 outperforms p-tau181 as a biomarker of Alzheimer’s disease co-pathology in the Lewy Body Disorders spectrum
Objective: To evaluate the relative performance of plasma p-tau217 and p-tau181 as biomarkers of Alzheimer’s disease (AD) co-pathology across the Lewy body disorders (LBD) spectrum.…DTI-Based Comparative Analysis of Microstructural Alterations in Parkinson Disease and Atypical Parkinsonism
Objective: Diffusion tensor imaging (DTI) holds promising potential for investigating pathological changes in white matter (WM). In recent years, numerous studies worldwide have demonstrated that…7 Tesla MRI with Quantitative Susceptibility Mapping: Quantitative focal measurements and qualitative grading of the substantia nigra as a biomarker for Parkinson’s Disease
Objective: To quantitatively and qualitatively evaluate susceptibility changes in the dorsal SN (dSN), using quantitative susceptibility mapping (QSM) and susceptibility-weighted imaging (SWI) at 7Tesla (7T)…Basal Ganglia Lacunar Infarcts and Risk of Mortality and Dementia in Parkinsonism: A Population-Based Study
Objective: To determine the prevalence of chronic basal ganglia lacunar infarcts (BGLI) and examine their association with dementia and mortality in a population-based cohort of…Remaining unmet needs in Essential Tremor and Parkinson’s Disease: European Neurologists’ Assessments of Pharmacologic Response and Advanced Therapy Use
Objective: To investigate neurologists’ perceptions of treatment effectiveness and criteria for selecting patients for advanced therapies in essential tremor (ET) and Parkinson’s disease (PD). Background:…Differential Cholinergic White Matter Microstructural Alterations in Multiple System Atrophy and Parkinson’s Disease
Objective: To investigate the extent and pattern of microstructural alterations of cholinergic pathways in MSA and PD. Background: MSA and PD are both α-synucleinopathies with…A Diffusion MRI Neurodegeneration Index for Lewy Body Dementia & Alzheimer’s disease
Objective: To develop a diffusion MRI-based neurodegeneration index using free-water imaging and assess its ability to quantify neurodegenerative burden in Lewy body dementia (LBD) and…Redefining Anatomical Boundaries, An Atypical Case of MV-PLUS with Supratentorial extension.
Objective: To report the first case of Multinodular and Vacuolating Posterior Fossa Lesions of Unknown Significance (MV-PLUS) with atypical supratentorial temporal extension, expanding the known…The utility of HbA1c in Predicting Neuroimaging Findings in Diabetic Striatopathy – A Systematic Review
Objective: To explore the impact of HbA1c on imaging in Diabetic Striatopathy. Background: Diabetic Striatopathy (DS) is a rare neurological complication of hyperglycemia. While glycemic…PET Imaging of Presynaptic Terminals with [18F]SynVesT-1 in Premanifest Huntington’s Disease
Objective: To assess synapse loss in vivo in late premanifest Huntington’s disease (HD) subjects using [18F]SynVesT-1 positron emission tomography (PET). Background: Synaptic damage is believed…
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