Brain Energetics: Changes in Healthy Aging and Parkinson’s Disease
Objective: To identify in vivo bioenergetic alterations in healthy aging and Parkinson’s disease (PD). Background: PD-related cerebral metabolic alterations have been robustly characterized [1] and…Clinical and neuro-imaging predictors of falls in PLA2G6-related Parkinsonism: a retrospective study
Objective: This study investigates clinical and neuroimaging predictors of recurrent falls and gait disturbances in PLA2G6-related Parkinsonism. Background: PLA2G6-related Parkinsonism is characterized by dystonia-parkinsonism, cerebellar…Association between Imaging Glymphatic Dysfunction Markers and Clinical Symptoms in Progressive Supranuclear Palsy
Objective: This study aims to explore possible glymphatic dysfunction using diffusion tensor image analysis along the perivascular space (DTI-ALPS) in patients with progressive supranuclear palsy…Clinical and paraclinical aspects of extrapyramidal disorders in patients with cerebrovascular pathology
Objective: To study of clinical and paraclinical aspects of extrapyramidal disorders in patients with cerebrovascular pathology Background: A considerable proportion of patients with chronic cerebral…Decoding Parkinson’s Progression: Longitudinal Volumetric MRI Biomarkers in Prodromal and Clinical Stages
Objective: This study investigates MRI volumetric analysis via VBM as a biomarker for early PD detection, focusing on structural alterations in deep gray matter regions…Linking Adolescent Brain Development To Parkinson’s Disease Risk Using Machine Learning On Polygenic Risk Scores
Objective: Examine whether adolescent brain structural deviations contribute to Parkinson’s disease (PD) susceptibility. Background: Genetic variants associated with PD have been linked to neurodevelopmental processes,…Differentiating White-Matter Damage Patterns by Underlying Pathology in Corticobasal Syndrome
Objective: This study aims to describe the patterns of white-matter damage using diffusion tensor imaging (DTI) in individuals with Corticobasal Syndrome (CBS) and compare the…A RNF213 truncating variant causes an autosomal dominant disorder with brainstem and basal ganglia lesions and a Huntington-like phenotype
Objective: To report a novel stop-gain variant in the RNF213 gene in two individuals, a father and son, presenting with variable neurologic presentations and similar…Prevalence and Clinical Characteristics of iNPH-Related Imaging Findings (DESH) in Parkinson’s Disease
Objective: To investigate the prevalence of idiopathic normal pressure hydrocephalus (iNPH)-related imaging findings (DESH) and their clinical characteristics in Parkinson’s disease (PD) patients. Background: PD…Minimally Invasive Magnetic Resonance Imaging guided Deep Brain Stimulation for Movement Disorders – A Novel technique, Accuracy and Clinical Outcome.
Objective: To study the accuracy of lead placement and clinical outcome of a novel technique using twist drill hole and smaller incision in Magnetic resonance…
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