Analyzing early states of HD progression using a machine learning driven approach
Objective: Our aim is to build an early state HD progression model (EHDPM), a sub-model to Integrated Huntington’s Disease Progression Model (IHDPM) [1] to identify…Eye-of-the-Tiger sign in Progressive Supranuclear Palsy
Objective: To present a rare case of eye-of-the-tiger sign in a patient with progressive supranuclear palsy (PSP). Background: The eye-of-the-tiger is a neuroradiologic sign appearing…Gray matter volumetry, cortical thickness and cognitive performance in treated Parkinson’s disease with REM sleep behavior disorder symptomatology
Objective: To explore MRI subcortical and cortical gray matter measures, as well as cognitive performance, in treated PD patients with REM sleep behavior disorder (RBD)…Nigral microvasculature imaging in Parkinson’s disease
Objective: The goal of this work is to image the microvasculature of the midbrain, in particular the substantia nigra in Parkinson’s disease (PD) patients using…Longitudinal white matter microstructural changes in the prodromal phase of PD: A 2 year prospective study
Objective: To prospectively investigate white matter (WM) alterations in non-manifesting carriers (NMCs) of Parkinson's disease (PD)-related mutations, and its association with likelihood ratio (LR) scores.…To scan or not to scan? Parkinsonian syndrome due to supratentorial glioblastoma
Objective: To present a rare case of asymmetric Parkinson disease (PD) due to a secondary structural lesion. Background: PD is a neurodegenerative disease characterized by…PD-MCI is frequent in candidates to subthalamic deep brain stimulation and is associated with structural brain alterations
Objective: To determine the prevalence of mild cognitive impairment (PD-MCI) in Parkinson's disease (PD) patients, candidates to subthalamic deep brain stimulation (STN-DBS) as well as the frequency…Pons and middle cerebellar peduncle diameters are diagnostic of Multiple System Atrophy of the Cerebellar Type (MSA-C)
Objective: To develop an MRI biomarker for the definitive diagnosis of Multiple System Atrophy of the Cerebellar Type (MSA-C). Background: MSA is a sporadic, adult-onset…Adults with slowly progressive dystonia-parkinsonism secondary to manganese accumulation
Objective: To expand the clinical spectrum of manganese-induced neurodegeneration. Background: Neurodegeneration induced by manganese accumulation is a potentially treatable condition and therefore should not be…The brain-age framework in Parkinson’s disease: evaluating MRI morphometry and sex-dimorphism
Objective: We aimed to develop an MRI brain-age prediction (BAP) model to evaluate differences between Parkinson’s disease (PD) and healthy controls (HC). We further evaluated…
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