Theoretical Definition of DBS Electrode Misplacement
Objective: To propose a definition of Subthalamic Nucleus Deep Brain Stimulation (STN-DBS) electrode misplacement (MP) based on ideal brain connectivity strength. Background: MP is defined…Cardio-respiratory fitness is associated with corticospinal excitability and motor learning in Parkinson’s Disease.
Objective: To explore associations between cardio-respiratory fitness (VO2peak), cortico-spinal excitability (CSE) and motor learning in people with Parkinson's Disease (PwPD). Background: PwPD show alterations in…Association between fine motor function and brain structure: Findings from the population-based Rhineland Study
Objective: To examine the relation between brain structure and fine motor function across adult lifespan in a large cohort study. Background: Decreased fine motor function…Investigation of superficial brain stimulation (SBS) in Parkinsonian rats as a non-invasive alternative treatment for patients with movement disorders
Objective: To investigate repetitive transcranial magnetic stimulation (rTMS) in parkinsonian rats as a non-invasive, malleable superficial brain stimulation (SBS) alternative to DBS. Background: DBS is…Measures of trancranial magnetic evoked potentials for prediction of response to ventriculoparitoneal shunt In normal pressure hydrocephalus
Objective: Assess the utility of an EEG-TMS-based evaluation for prediction of response to ventriculoperitoneal shunt (VPS) in normal pressure hydrocephalus (NPH). Background: VPS is the…Action verb use in PD: A challenge to the embodied cognition hypothesis?
Objective: To characterize action verb production in Parkinson's disease (PD) during a picture description task, and evaluate associations with motor and cognitive function. Background: The…A mouse model to test the cortical pathogenic theory of Parkinson’s disease
Objective: To develop a mouse model of chronic corticostriatal overactivity and increase expression of corticostriatal alpha-synuclein. Background: Parkinson’s disease typically has a focal motor onset1,…Cortical and cerebellar excitability in essential tremor
Objective: To investigate the functional state of motor cortex excitability and the involvement of the cerebello-thalamo-cortical pathway using transcranial magnetic stimulation (TMS) in patients with…Reducing corticospinal excitability with transcranial static magnetic field stimulation
Objective: To investigate the potential of transcranial static magnetic field stimulation (tSMS) for reducing corticospinal excitability when delivered to the primary motor cortex (M1) or…Home-based transcranial static magnetic field stimulation of the motor cortex for treating levodopa-induced dyskinesias in Parkinson’s disease
Objective: To investigate the potential of transcranial static magnetic field stimulation (tSMS) as a non-pharmacological, non-invasive, home-based treatment to manage levodopa-induced dyskinesias (LIDs) in Parkinson’s…
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