A composite oculomotor biomarker for differentiating Parkinson’s disease from multiple system atrophy
Objective: To evaluate whether a composite oculomotor index integrating multiple eye movement domains improves discrimination between PD and MSA. Background: Differentiating Parkinson’s disease (PD) from…Clinical Significance of Imaging Markers for Cerebellar Ataxia and Parkinsonism in Multiple System Atrophy
Objective: To clarify the interactions among clinical features and imaging markers, and to identify factors contributing to disease severity in MSA. Background: Multiple system atrophy…Assessment of dysautonomia in patients with sporadic adult-onset ataxia
Objective: The aim of this study was to assess prevalence and severity of autonomic dysfunction in patients with SAOA, defined as a subacute or progressive…Multi-Sequence MRI-Based Machine Learning Model for Differentiating Parkinson Disease (PD) from Multiple System Atrophy (MSA)
Objective: To develop a multi-sequence MRI-based machine learning model differentiating PD from MSA. Background: MRI protocols capable of distinguishing PD from MSA are greatly needed.…Determinants of Re-diagnosis of Parkinson’s Disease to Atypical Parkinsonism: Results from the Tracking Parkinson’s Cohort (PRoBAND) and Oxford Parkinson’s Discovery Cohort (OPDC) Cohorts
Objective: We aim to identify the clinical and biomarker features which best predict re-diagnosis to a Parkinson plus syndrome (PPS) in those initially diagnosed with…Choroid Plexus Morphology and Enhancement as Imaging Markers for Early Differentiation of Multiple System Atrophy and Parkinson’s Disease
Objective: To characterize choroid plexus (ChP) morphology and enhancement in multiple system atrophy (MSA) and Parkinson’s disease (PD), investigate their associations with ventricular morphology and…Real-World Survival, Healthcare Access, and Medication Patterns in Atypical Parkinsonian Disorders: A Multi-System EHR Analysis
Objective: To assess regional prevalence, demographics, survival, neurology access, and medication utilization in atypical parkinsonian disorders. Background: Progressive supranuclear palsy (PSP), corticobasal syndrome (CBS), and…Pain in Multiple System Atrophy: a healthcare professionals’ survey
Objective: To appraise current knowledge, screening and treatment habits on pain in multiple system atrophy (MSA) among allied healthcare professionals (HCPs). Background: Pain is a…Cortical Mean Diffusivity as a Measure of Microstructural Neurodegeneration in Multiple System Atrophy
Objective: To characterize cortical microstructural alterations in multiple system atrophy (MSA) and to examine their associations with clinical features and neuropsychological performance. Background: Cortical mean…Dynamic and Multimodal Prediction of Phenoconversion to Cerebellar Multiple Sytem Atrophy among Sporadic Late-Onset Cerebellar Ataxia
Objective: To dynamically predict phenoconversion from a sporadic late-onset cerebellar ataxia (SLOCA) phenotype to MSA-C. Background: Cerebellar multiple system atrophy (MSA-C) is diagnosed according to…
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