Is Urinary Retention a Marker of Possible Prodromal MSA in PAF?
Objective: This study aims to evaluate the role of post-void urinary residual volume (PVR) in Pure Autonomic Failure (PAF) and its prognostic value as a…Proteomic analysis identifies GGA1, SCP2, and RABEPK as risk protein of multiple system atrophy
Objective: Investigating proteomic changes preceding MSA onset to provide critical insights into disease biology, uncover novel biomarkers for early detection, and identify potential therapeutic targets.…Cutaneous Phosphorylated Alpha-Synuclein Deposition in Multiple System Atrophy
Objective: To report differences in the amount, localization and topographic distribution of cutaneous P-SYN deposition between cerebellar and parkinsonian variants of MSA. Background: MSA is…Predictive clinical factors for the faster progression from idiopathic late-onset cerebellar ataxia to multiple system atrophy cerebellar type
Objective: Our study aims to investigate the clinical parameters associated with faster conversion from late-onset cerebellar ataxia (ILOCA) to multiple system atrophy cerebellar type (MSA-C)…Clinical and Dopaminergic Characteristics of MSA-C Patients with Predominant Cerebellar Asymmetry
Objective: To identify multiple system atrophy–cerebellar type (MSA-C) patients with marked cerebellar asymmetry and compare their features with symmetrically affected patients. Background: While asymmetry is…Differences Between Clinical and Imaging Phenotypes in Phase 2 Study of ATH434 in Multiple System Atrophy
Objective: To assess differences between clinical and imaging phenotypes in Multiple System Atrophy (MSA) and evaluate the reliability of imaging biomarkers for subtype classification. Background:…Functional Alterations in Early-Stage Parkinson’s Disease and Multiple System Atrophy with REM Sleep Behavior Disorder
Objective: This study investigated functional brain network alterations in early-stage Parkinson’s disease (PD) and multiple system atrophy (MSA) patients with probable rapid eye movement sleep…Brain perfusion patterns associated with motor symptoms in multiple system atrophy
Objective: There is a need for objective methods to assess disease progression in multiple system atrophy (MSA). This study aimed to identify brain perfusion patterns…The Role of FGF14 GAA Repeat Expansions in Multiple System Atrophy: Frequency, Phenotypic Correlations, and Prognostic Implications
Objective: This study aimed to investigate the frequency of FGF14 GAA•TTC repeat expansion in clinically diagnosed and pathologically confirmed multiple system atrophy cases. Background: Partial…Retrospective analysis of MSA diagnosis in a neuroscience hospital
Objective: We evaluated the extent to which diagnoses of MSA align with the MDS criteria within a specialist neurology trust in the UK. We aimed…
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