Ultra-early Diagnosis of MSA-C Using Biological Biomarkers: A Two-Case Study Employing α-Synuclein PET and Fluid α-Synuclein Seeds Amplification Assay (SAA)
Objective: To report cases in which combined α-synuclein PET and body fluid α-synuclein seeds amplification assay (SAA) enabled biological diagnosis of multiple system atrophy–cerebellar type…Novel Structural MRI-Based Progression Subtypes and Prognostic Study in Multiple System Atrophy
Objective: To identify structural MRI-based progression subtypes in multiple system atrophy (MSA) and determine whether these imaging-defined subtypes are associated with distinct clinical features, molecular…Diagnostic Delay in Multiple System Atrophy: Sociodemographic and Clinical Predictors in a Single-Center Cohort
Objective: To evaluate sociodemographic and clinical predictors of diagnostic delay in multiple system atrophy (MSA) at a single tertiary referral center. Background: MSA is a…Local Glymphatic Dysfunction in Multiple System Atrophy: Insights from Multimodal MRI
Objective: To evaluate multimodal glymphatic-related MRI proxies in multiple system atrophy (MSA) and explore their relationship with clinical features. Background: Impaired fluid transport and waste…Distinct FDG-PET metabolic patterns and connectivity alterations in dopamine transporter-deficient versus -preserved MSA-C
Objective: In this study, we stratified MSA-C patients by DaT-PET binding status (preserved vs deficient) and compared their 18F-FDG PET metabolic patterns and inter-regional metabolic…Clinicogenetic Characterization of Sporadic Adult-Onset Ataxias in Austria
Objective: To gain insight in the natural history of sporadic adult-onset ataxia (SAOA), identify unrecognized genetic underpinnings and improve early differentiation from other causes of…Micrographia in Parkinson’s Disease and Multiple System Atrophy: A Quantitative Tablet-Based Handwriting Study
Objective: To evaluate the relative contributions of cognitive and motor factors to handwriting performance in patients with MSA and PD using quantitative tablet-based tasks. Background:…Differential Cholinergic White Matter Microstructural Alterations in Multiple System Atrophy and Parkinson’s Disease
Objective: To investigate the extent and pattern of microstructural alterations of cholinergic pathways in MSA and PD. Background: MSA and PD are both α-synucleinopathies with…Exploring Swallowing Dysfunction, Quality of Life, and Caregiver Burden in Multiple System Atrophy
Objective: To investigate associations between swallowing-related symptoms and disease severity, quality of life, and caregiver burden in patients with MSA in a large UK-based cohort.…Clinical Correlates of Dysphagia in Multiple System Atrophy: A Multicenter Retrospective Study
Objective: To identify clinical factors associated with dysphagia severity in patients with MSA. Background: Dysphagia is a common and clinically important complication in multiple system…
- 1
- 2
- 3
- …
- 28
- Next Page »