Functional Alterations in Early-Stage Parkinson’s Disease and Multiple System Atrophy with REM Sleep Behavior Disorder
Objective: This study investigated functional brain network alterations in early-stage Parkinson’s disease (PD) and multiple system atrophy (MSA) patients with probable rapid eye movement sleep…Brain perfusion patterns associated with motor symptoms in multiple system atrophy
Objective: There is a need for objective methods to assess disease progression in multiple system atrophy (MSA). This study aimed to identify brain perfusion patterns…The Role of FGF14 GAA Repeat Expansions in Multiple System Atrophy: Frequency, Phenotypic Correlations, and Prognostic Implications
Objective: This study aimed to investigate the frequency of FGF14 GAA•TTC repeat expansion in clinically diagnosed and pathologically confirmed multiple system atrophy cases. Background: Partial…Retrospective analysis of MSA diagnosis in a neuroscience hospital
Objective: We evaluated the extent to which diagnoses of MSA align with the MDS criteria within a specialist neurology trust in the UK. We aimed…Novel Multiple System Atrophy Subtypes Identified Using Unsupervised Machine Learning Algorithms
Objective: To identify a novel disease subtype of multiple system atrophy (MSA) by applying machine learning algorithms to a large cohort of autopsy-confirmed MSA. Background:…Natural history and epidemiological study of multiple system atrophy in Hokkaido: HoRC-MSA 2014-2025
Objective: To investigate epidemiological information of multiple system atrophy (MSA) patients in Hokkaido, Japan by using the registry data from the Hokkaido Rare-disease Consortium for…Intrathecal Administration of Human Oral Mucosa Neural Crest Stem Cells in Moderate/Advanced Multiple System Atrophy: Report on Ongoing Phase 1 Study
Objective: This first-in-human study aims to evaluate the safety of hOMNSC300 following intrathecal administration in patients with moderate to advanced MSA. Background: Stem cell therapy…Longitudinal FDG-PET Study of Metabolic Trajectories and Connectivity Alterations in Multiple System Atrophy
Objective: 本研究使用 FDG-PET 探索 MSA 中葡萄糖代谢和网络连接的纵向变化，以辅助早期诊断和监测疾病进展。 Background: Multiple system atrophy (MSA) is a rapidly progressive neurodegenerative disease with distinct metabolic patterns in its parkinsonian (MSA-P)…Neurogenic bladder and affective disorders in parkinsonism
Objective: To determine the relationship between psychoemotional and dysuria dysfunctions in patients with PD and MSA. Background: In the group of patients with extrapyramidal pathology…Balance confidence may not accurately assess fall risk in atypical parkinsonism
Objective: Objective: To examine if balance confidence, measured by the Activities-specific Balance Confidence (ABC) scale, reflects fall frequency in atypical parkinsonian syndromes (APS), namely multiple…
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