MDS Abstracts

Abstracts from the International Congress of Parkinson’s and Movement Disorders.

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Articles tagged "Multiple system atrophy(MSA): Clinical features"

  • 2026 International Congress

    Diagnostic Utility of Routine 1.5T Brainstem Planimetry in Parkinsonism: Evidence from a Vietnamese Cohort

    D. Nguyen, T. Tran (St Lucia, Australia)

    Objective: To compare absolute versus ratio brainstem planimetric measures on routine 1.5T MRI and to identify the best-performing metrics for differentiating PSP and MSA in…
  • 2026 International Congress

    Psychometric Assessment of a Modified Version of the Unified Multiple System Atrophy Rating Scale Part I

    AK. Berger, A. Rieckmann, K. Nighah, S. Zanigni (Valby, Denmark)

    Objective: To evaluate the psychometric properties, reliability, and validity of a modified version of UMSARS Part I (mUMSARS), collapsing response categories 0 and 1 and…
  • 2026 International Congress

    Biomarker-Informed Survival Modelling Using Plasma Neurofilament Light and Clinical Predictors in a Prospective Multiple System Atrophy Cohort

    V. Chelban, L. Lei, C. Lee, Y. Goh, I. Karagoz, R. Lee, H. Morris, N. Vijiaratnam, T. Foltynie, H. Houlden (London, United Kingdom)

    Objective: To develop and evaluate multimodal survival models in MSA integrating clinical features with plasma NfL. Background: Progression in Multiple System Atrophy (MSA) is highly heterogeneous. Robust…
  • 2026 International Congress

    A prospective single-center study investigating the utility of supportive features in the diagnosis of multiple system atrophy with predominant cerebellar ataxia

    A. Sugiyama, Y. Nakagawa, M. Namiki, S. Hirano, Y. Nakano, T. Yamamoto, Y. Yamanaka, M. Mori (Chiba, Japan)

    Objective: The present study aimed to determine the utility of supportive motor and nonmotor features in differentiating multiple system atrophy (MSA) with predomainat cerebellar ataxia…
  • 2026 International Congress

    Validation of the Chinese Version of the Unified Multiple System Atrophy Rating Scale

    AK. Berger, A. Rieckmann, D. Oudin ǻström, S. Zanigni, Q. Zhou, T. Feng, H. Wang, J. Wang, B. Tang, CF. Liu, H. Chen, W. Mao, P. Chan, H. Shang, L. Cui (Valby, Denmark)

    Objective: To assess the psychometric properties of the Chinese version of the Unified Multiple System Atrophy Rating Scale (UMSARS). Background: The UMSARS is the gold‑standard…
  • 2026 International Congress

    Divergent Glymphatic Dysfunction and Free Water Pathology Underpin Distinct Mechanisms and Enable Differential Diagnosis in Parkinson’s Disease and Multiple System Atrophy

    RNS. Shen, LCZ. Zhou, JL. Liu (Shanghai, China)

    Objective: To evaluate glymphatic function and FW pathology in PD and MSA, and to develop an integrated biomarker panel for differential diagnosis. Background: Parkinson's disease…
  • 2026 International Congress

    Pattern and progression of sudomotor dysfunction in alpha synucleinopathies

    Z. Jiang, G. Chiaro, V. Iodice (London, United Kingdom)

    Objective: This study examined the distribution and longitudinal progression of sweat loss in patients with PAF. Background: Pure autonomic failure (PAF) is an alpha-synucleinopathy with…
  • 2026 International Congress

    Automated Speech Analysis for the Differentiation of Multiple System Atrophy from Parkinson’s Disease in an English-Speaking Cohort

    E. Ní Chonchúir, C. Espinoza Vinces, X. Yang, C. O'Keeffe, J. Inocentes, A. Gill, C. Fearon, R. Reilly (Dublin, Ireland)

    Objective: The aim of this pilot study was to determine whether automatically extracted speech features, derived from targeted speech tasks, can differentiate Multiple System Atrophy…
  • 2026 International Congress

    Automated Differentiation for Early Parkinsonism Using Clinical Structural MRI: A Multicenter Study

    LC. Zhou, CZ. Wang, AL. Du, J. Liu, J. Wang (Shanghai, China)

    Objective: To develop and validate a T1-weighted structural MRI–based machine learning model for differentiating Parkinsonism at early-to-mid stage and generalize the model to routine anisotropic…
  • 2026 International Congress

    Beyond Diagnosis: Putaminal ADC Hyperintensity and Infratentorial Signs Reflect Motor Severity in MSA

    Y. Zhao, K. Li, Y. Zheng, M. Luan, H. Tang, C. He, J. Liu, F. Li, L. Wei, J. Chen, W. Sun, J. Deng, Z. Wang, Y. Zhu, Y. Sun (Beijing, China)

    Objective: To clarify the clinical significance of neuroimaging markers in multiple system atrophy (MSA) by (1) examining concordance among putaminal MRI markers across sequences, (2)…
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