Real world application of alpha-synuclein skin biopsy in the diagnosis of synucleinopathies at a tertiary care center
Objective: The goal of this study is to review the real-world application of alpha-synuclein skin biopsy at a tertiary care center. Background: Synucleniopathies including Parkinson’s…Is Urinary Retention a Marker of Possible Prodromal MSA in PAF?
Objective: This study aims to evaluate the role of post-void urinary residual volume (PVR) in Pure Autonomic Failure (PAF) and its prognostic value as a…Proteomic analysis identifies GGA1, SCP2, and RABEPK as risk protein of multiple system atrophy
Objective: Investigating proteomic changes preceding MSA onset to provide critical insights into disease biology, uncover novel biomarkers for early detection, and identify potential therapeutic targets.…Cutaneous Phosphorylated Alpha-Synuclein Deposition in Multiple System Atrophy
Objective: To report differences in the amount, localization and topographic distribution of cutaneous P-SYN deposition between cerebellar and parkinsonian variants of MSA. Background: MSA is…Predictive clinical factors for the faster progression from idiopathic late-onset cerebellar ataxia to multiple system atrophy cerebellar type
Objective: Our study aims to investigate the clinical parameters associated with faster conversion from late-onset cerebellar ataxia (ILOCA) to multiple system atrophy cerebellar type (MSA-C)…Clinical and Dopaminergic Characteristics of MSA-C Patients with Predominant Cerebellar Asymmetry
Objective: To identify multiple system atrophy–cerebellar type (MSA-C) patients with marked cerebellar asymmetry and compare their features with symmetrically affected patients. Background: While asymmetry is…Differences Between Clinical and Imaging Phenotypes in Phase 2 Study of ATH434 in Multiple System Atrophy
Objective: To assess differences between clinical and imaging phenotypes in Multiple System Atrophy (MSA) and evaluate the reliability of imaging biomarkers for subtype classification. Background:…Pain types in multiple system atrophy: results from a community-based survey
Objective: To assess the frequency of different pain types in multiple system atrophy (MSA). Background: According to a recent meta-analysis, up to 60% of individuals…Whole-brain functional network signature reflecting conversion of isolated REM sleep behavior disorder
Objective: The aim was to investigate the brain functional network alteration /pattern as a measure to identify the conversion from idiopathic rapid eye movement sleep…Multiple System Atrophy in a Patient with Normal Pressure Hydrocephalus
Objective: To review a case of a patient diagnosed with both NPH and MSA. Background: Multiple system atrophy (MSA) is a progressive neurodegenerative disease that…
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