Effects of mannitol treatment in a mice model of multiple system atrophy (MSA)
Objective: The aim of this study was to examine the effect of mannitol treatment in a mice model of MSA. Background: Alpha-synuclein aggregation represents the…Serum cholesterol level is associated with risk of MSA
Objective: We aim to ascertain the association between serum cholesterol and multiple system atrophy (MSA). Background: MSA, a common form of atypical parkinsonism, is a…To Study the Role of Biomarkers DJ-1 and Apo A1 in Idiopathic Parkinson’s Disease and Parkinson Plus Syndromes in Indian Population
Objective: To study the role of serum DJ-1 and Apo A1 in the diagnosis and differentiation of Idiopathic Parkinson Disease (IPD) and Parkinson Plus Syndromes(PPS)…Viral-mediated oligodendroglial alpha-synuclein expression models multiple system atrophy
Objective: We aimed to develop AAV-based models of MSA Background: Multiple system atrophy (MSA) is a fatal neurodegenerative disorder characterized by a combination of autonomic…Profound reduction of DAT-SPECT signal in multiple system atrophy (MSA)
Objective: To evaluate the extent of degeneration in dopamine nerve terminal in striatum in the patients with MSA-P and MSA-C, and to compare the progression…Cardiac Autonomic Dysregulation in Probable Multiple System Atrophy
Objective: The objective was to retrospectively study the nature of cardiac autonomic dysfunction and the effect of phenotype on it in probable Multiple System Atrophy…Metabolomics study in a group of Parkinson’s disease patients from Northern India
Objective: To do (1) H NMR study in a group of Parkinson’s disease patients, disease controls, viz. multiple system atrophy (MSA) and progressive supra nuclear…Antibody binding differences in alpha-synuclein from Parkinson’s disease and multiple system atrophy
Objective: Determine whether alpha-synuclein derived from Parkinson's disease (PD) and multiple system atrophy (MSA) brains has different conformations as defined by biochemical and antibody-based approaches. Background: There…MRI-based Brain Networks of Perfusion and Structural Abnormalities in Patients with Cerebellar Variant of Multiple System Atrophy
Objective: To identify MRI-based brain networks of cerebral perfusion and structural abnormalities in cerebellar variant of MSA. Background: MSA consists clinically of parkinsonian (MSA-P) and cerebellar (MSA-C) variants. Previous FDG PET studies have…Specific Metabolic Brain Networks Associated with Parkinsonian and Cerebellar Variants of Multiple System Atrophy
Objective: To identify specific metabolic brain networks for parkinsonian (MSA-P) and cerebellar (MSA-C) variants of MSA. Background: MSA is associated with a disease-related metabolic brain network (MSARP)…
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