MDS Abstracts

Abstracts from the International Congress of Parkinson’s and Movement Disorders.

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Articles tagged "Neuromelanin"

  • 2019 International Congress

    Changes in Neuromelanin MRI Signal in Parkinson’s Disease: A Longitudinal Study

    R. Gaurav, L. Yahia-Cherif, G. Mangone, N. Pyatigorskaya, R. Valabregue, C. Ewenczyk, M. Hutchison, J. Corvol, M. Vidailhet, S. Lehéricy (Paris, France)

    Objective: To investigate the neuromelanin (NM) signal changes in Parkinson’s disease (PD) patients associated with disease progression. Background: PD is characterized by the progressive loss…
  • 2019 International Congress

    Investigation of 531 cases of neuromelanin sensitive imaging, about its characteristics by disease

    K. Matsuura, Y. Ii, M. Maeda, K. Tabei, M. Umino, H. Tomimoto (Tsu, Japan)

    Objective: To investigate the utility of Neuro-Melanin sensitive MRI (NMI) by 3T MRI for diagnosis, the relationship and severity in Parkinson's disease (PD) and related…
  • 2018 International Congress

    Neuromelanin Imaging and Midbrain Volumetry in Progressive Supranuclear Palsy and Parkinson’s Disease

    D. Taniguchi, T. Hatano, K. Kamagata, A. Okuzumi, M. Hori, S. Aoki, N. Hattori (Tokyo, Japan)

    Objective: Using neuromelanin-sensitive magnetic resonance imaging (NM-MRI) and midbrain volumetry, we analyzed differences and relationships between nigral degeneration and midbrain atrophy in PSP and PD…
  • 2018 International Congress

    Longitudinal changes in Neuromelanin MRI Signal in Parkinson’s Disease

    R. Gaurav, N. Pyatigorskaya, C. Ewenczyk, R. Valabregue, K. Evans, I. Arnulf, M. Vidailhet, S. Lehéricy (Paris, France)

    Objective: To examine the longitudinal changes in neuromelanin (NM) MRI signal in the substantia nigra (SN) in Parkinson’s disease (PD). Background: PD is characterized by…
  • 2018 International Congress

    Quantitative analysis of DaT uptake and neuromelanin MR contrast in patients with Parkinson’s disease and healthy controls

    D. Ben Bashat, M. Artzi, A. Mirelman, T. Thaler, A. Orr Urterger, M. Weisz, E. Even-Sapir, K. Evans, R. Hutchison, J. Cedarbaum, H. Lerman Shacham (Tel Aviv, Israel)

    Objective: To examined quantitative measures of neuromelanin (NM) MRI and DaT-SPECT imaging of the SN and striatum to distinguish PD patients from healthy control subjects…
  • 2018 International Congress

    Semi-automated segmentation and quantification of the substantia nigra depigmentation in Parkinson’s disease – a multicentre case control MRI study in 284 participants

    Y. Xing, S. Schwarz, A. Martin-Bastida, L. Parkes, H. Abdul-Sapuan, S. Naidu, M. Silverdale, D. Grosset, P. Piccini, D. Burn, N. Bajaj, N. Pavese, D. Auer (Nottingham, United Kingdom)

    Objective: To provide a semi-automated segmentation and quantification method of the changes in the substantia nigra (SN) in Parkinson’s disease (PD) using neuromelanin (NM)-sensitive MRI…
  • 2017 International Congress

    Neuromelanin Magnetic Resonance Imaging of the Substatia Nigra in LRRK2 -related Parkinson’s disease

    L. Correia Guedes, S. Reimão, P. Paulino, R. Nunes, R. Bouça, D. Abreu, N. Gonçalves, T. Soares, M. Fabbri, C. Godinho, P. Lobo, D. Neutel, M. Quadri, M. Coelho, M.M. Rosa, J. Campos, T. Outeiro, C. Sampaio, V. Bonifati, J. Ferreira (Lisbon, Portugal)

    Objective: Our study aimed to evaluate neuromelanin-Magnetic Resonance signal changes in PD patients carrying a LRRK2 mutation. Background: Specific magnetic resonance (MR) sequences are able to…
  • 2017 International Congress

    [18F]-AV-1451 binding to neuromelanin in the substantia nigra in PD and PSP

    S. Coakeley, S.S. Cho, Y. Koshimori, P. Rusjan, A. Lang, S. Houle, A. Strafella (Toronto, ON, Canada)

    Objective: This study was designed to investigate the binding of [18F]-AV-1451 to neuromelanin in parkinsonisms. Uptake in the substantia nigra of Parkinson’s disease (PD) and…
  • 2017 International Congress

    Substantia nigra area evaluated by neuromelanin-sensitive MRI as an imaging biomarker of disease progression in Parkinson’s disease

    M. Fabbri, S. Reimão, M. Carbalho, R. Nunes, D. Abreu, L. Guedes, R. Bouça, P. Lobo, C. Godinho, M. Coelho, N. Gonçalves, M. Rosa, A. Antonini, J. Ferreira (Lisbon, Portugal)

    Objective: to investigate the pattern of substantia nigra - neuromelanin (SN-NM) area loss and contrast ratio (CR) intensity changes in late-stage Parkinson’s disease (LSPD) patients,…
  • 2016 International Congress

    Prognostic factors of motor symptoms in Parkinson’s disease using neuromelanin imaging and the relationship with (123)I-FP-CIT-SPECT

    A. Okuzumi, T. Hatano, K. Kamagata, M. Hori, S. Aoki, N. Hattori (Tokyo, Japan)

    Objective: This study aimed to examine the relationship between findings of neuromelanin sensitive MRI findings and motor complications. We also examined the correlation of findings…
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