Neuromelanin MRI detects monoaminergic cell loss in Huntington Disease Expansion Gene Carriers.
Objective: To measure, with NM-MRI, the integrity of neuromelanin-containing monoaminergic cells in the SN and LC in Huntington Disease Gene Expansion Carriers (HDGECs) and compare…Sequencing of single human nigral dopaminergic neurons for somatic copy number variants
Objective: To detect somatic DNA copy number variants (CNVs) in dopaminergic neurons isolated from human substantia nigra, using shallow whole genome sequencing (WGS). Background: Somatic…Neuromelamin-MRI in patients with Pure Autonomic Failure
Objective: To assess the utility of neuromelanin-MRI (NM-MRI) methods in a prodromal alpha-synuclein disorder, Pure Autonomic Failure (PAF). Background: PAF is a peripheral alpha-synucleinopathy (AS)…Depressive Symptoms are Associated with Lower Locus Coeruleus Volumes in Parkinson’s disease
Objective: To assess locus coeruleus volumes in Parkinson's disease patients with depressive symptoms. Background: Depression associated with Parkinson disease (PD) has a different symptom profile…Imaging biomarker for progression of motor symptoms in advanced Parkinson’s disease
Objective: The aim of the present study is to clarify correlation between motor deficits and dopaminergic neuronal loss in advanced Parkinson’s disease (PD). Background: Series…Changes in Neuromelanin MRI Signal in Parkinson’s Disease: A Longitudinal Study
Objective: To investigate the neuromelanin (NM) signal changes in Parkinson’s disease (PD) patients associated with disease progression. Background: PD is characterized by the progressive loss…Investigation of 531 cases of neuromelanin sensitive imaging, about its characteristics by disease
Objective: To investigate the utility of Neuro-Melanin sensitive MRI (NMI) by 3T MRI for diagnosis, the relationship and severity in Parkinson's disease (PD) and related…Neuromelanin Imaging and Midbrain Volumetry in Progressive Supranuclear Palsy and Parkinson’s Disease
Objective: Using neuromelanin-sensitive magnetic resonance imaging (NM-MRI) and midbrain volumetry, we analyzed differences and relationships between nigral degeneration and midbrain atrophy in PSP and PD…Longitudinal changes in Neuromelanin MRI Signal in Parkinson’s Disease
Objective: To examine the longitudinal changes in neuromelanin (NM) MRI signal in the substantia nigra (SN) in Parkinson’s disease (PD). Background: PD is characterized by…Quantitative analysis of DaT uptake and neuromelanin MR contrast in patients with Parkinson’s disease and healthy controls
Objective: To examined quantitative measures of neuromelanin (NM) MRI and DaT-SPECT imaging of the SN and striatum to distinguish PD patients from healthy control subjects…
Abstracts from the International Congress of Parkinson’s and Movement Disorders.