Parkinson’s disease motor phenotypes delineated by pallidal and subthalamic neurophysiology and machine learning
Objective: The objective of this study was to develop a machine learning (ML) algorithm capable of predicting motor phenotypes in Parkinson's disease (PD) using intraoperative…Subthalamic β frequency oscillatory activity is modulated by self-paced wrist movement
Objective: To explore whether subthalamic β oscillatory neurons are associated with the initiation of voluntary movement in patients with Parkinson’s disease (PD). Background: The basal…Towards automated deep brain stimulation programming using neurophysiology and artificial intelligence
Objective: To develop a machine learning (ML) algorithm capable of predicting the optimal deep brain stimulation (DBS) contact based on neurophysiology. Background: DBS is an…TMS-EEG Provides Objective Neurophysiological Measures of Motor Fluctuations in Parkinson’s Disease
Objective: To assess the correlates TMS evoked potentials (TEPs) measurements changes representing interhemispheric transmission to the change in motor symptoms in 'off' versus 'on' states.…Frontal and Motor TMS Evoked Potentials Predict Response to Ventriculoperitoneal Shunt in NPH
Objective: Assess the ability of neurophysiological measure of TMS evoked potentials to predicts response to shunting in NPH. Background: NPH is an age-related condition of…Oculomotor Differences in PARK2 PD: a Study of Structured and Unstructured Eye Movements in an Irish Genetic Cohort
Objective: To identify and measure how eye movements differ between biallelic PARK2 carriers, carriers of a single PARK2 variant and non-carriers using structured and unstructured…Effects of Loading, Tapping Performance, and Ballistic Movements on Postural Tremor Features in Patients with Essential Tremor
Objective: To comprehensively evaluate the effects of loading, tapping performance, and ballistic movements on major tremor features in patients with essential tremor (ET). Background: In…Functional neurological disorders might be a frequent cause of slow orthostatic tremor: insights from a case series.
Objective: To study the clinical and electrophysiological characteristics of series of patients with slow orthostatic tremor (sOt) Background: sOT is characterized by tremor <13Hz affecting…Mechanical and thermal thresholds in the MPTP macaque model of Parkinson’s disease
Objective: To characterise the mechanical and thermal thresholds in the MPTP macaque model of Parkinson’s disease (PD). Background: Many PD patients suffer from some form…Sleep profiles in patients with Essential Tremor and Essential Tremor Plus: Polysomnography Insights
Objective: This study aims to assess sleep disturbances in Essential tremor (ET) and its variant, ET plus, compared to healthy controls using Polysomnography (PSG), and…
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