MDS Abstracts

Abstracts from the International Congress of Parkinson’s and Movement Disorders.

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Articles tagged "Olfactory dysfunction"

  • 2018 International Congress

    Risk estimation in the years preceding diagnosis of Parkinson’s disease in the PREDICT-PD cohort

    S. Auger, D. Rack, J. Bestwick, G. Giovannoni, A. Lees, A. Schrag, A. Noyce (London, United Kingdom)

    Objective: To test and refine the use of probability-based algorithms to identify individuals at high-risk of developing Parkinson’s disease (PD). Background: Neurodegeneration preceding a formal…
  • 2018 International Congress

    Olfactory dysfunction predicting cognition

    X. Yu (Cleveland, OH, USA)

    Objective: To investigate the relationship between impairment in smell and cognitive function among older adults using both self-report and objective measurement of olfactory function. Background:…
  • 2018 International Congress

    A53T mutant human α-synuclein BAC transgenic mice as a model for Parkinson’s disease

    T. Taguchi, I. Masashi, M. Uemura, Y. Hatanaka, N. Uemura, H. Yamakado, R. Takahashi (Kyoto, Japan)

    Objective: The aim of this study is to create mouse models reproducing the course of PD pathology and symptoms. Background: Parkinson's disease (PD) is a…
  • 2018 International Congress

    Olfactory impairment correlates strongly with limbic blood flow in patients with Parkinson’s disease

    K. Ohta, T. Nakajima (Niigata, Japan)

    Objective: To examine the cerebral blood flow pattern of patients of Parkinson's disease with olfactory disorders, and to investigate the correlation between olfactory impairment and…
  • 2018 International Congress

    Olfactory dysfunction, sleep disturbances, neuronal loss, and regional brain atrophy in an inducible mouse model of Alpha-Synucleinopathy

    E. Brison, S. Zehntner, A. Zijdenbos, K. Luk, B. Bedell (Montreal, QC, Canada)

    Objective: The objective of this work is to develop a unique mouse model of spreading α-synucleinopathy to accelerate the development of novel disease-modifying treatments for…
  • 2018 International Congress

    Association of Olfaction dysfunction with Brain Microstructure in Prodromal Parkinson disease

    H. Sanjari Moghaddam, M.H. Aarabi, Z. Valitabar (Tehran, Islamic Republic of Iran)

    Objective: Investigating the association between olfactory dysfunction and connectometry patterns in UPSIT-matched prodromal and PD patients. Background: Parkinson’s disease (PD) is a heterogeneous neurodegenerative disease…
  • 2018 International Congress

    Striatal dopamine uptake and olfactory dysfunction in patients with early Parkinson’s disease

    YS. Oh, DW. Ryu, JS. Kim, CH. Lyoo (Seoul, Republic of Korea)

    Objective: To identify dopamine transporter status of corpus striatum and thalamus using magnetic resonance imaging-guided spatial normalization method in patients with PD according to olfactory…
  • 2018 International Congress

    Clinical and imaging progression in the PARS cohort: Results from 6 years of observation

    D. Jennings, A. Siderowf, S. Eberly, D. Oakes, M. Stern, K. Marek (New Haven, CT, USA)

    Objective: The goal of the Parkinson Associated Risk Syndrome (PARS) study is to explore the clinical and biomarker trajectory of individuals in the pre-motor phase…
  • 2018 International Congress

    Diffusion tensor imaging of olfactory tract in Parkinson’s disease

    P. Nigro, N. Tambasco, A. Chiappiniello, S. Simoni, E. Brahimi, M. Romoli, F. Paolini Paoletti, M. Filidei, P. Calabresi (Perugia, Italy)

    Objective: We investigated the possible relationships among olfactory impairment and alterations in diffusion tensor imaging (DTI) of olfactory tracts, comparing a cohort of patients with…
  • 2018 International Congress

    Gender differences in olfactory dysfunctions in Sardinian patients affected by Parkinson’s disease

    P. Solla, C. Masala, A. Cannas, G. Defazio (Cagliari, Italy)

    Objective: To investigate the presence of specific gender-related patterns in olfactory dysfunctions among Sardinian patients affected by Parkinson's disease (PD), compared with age and sex-matched…
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