Efficacy and safety of zonisamide in patients with dementia with Lewy bodies with parkinsonism: pooled analysis of phase 2 and 3 trials
Objective: To characterize the efficacy and safety of zonisamide (ZNS) in patients with dementia with Lewy bodies (DLB) with parkinsonism, a pooled analysis of two…Biphasic Dyskinesias in Parkinson’s disease Patients treated with Levodopa/Carbidopa Intestinal Gel: Insights from a Multicenter Retrospective Analysis
Objective: We aimed to characterize Parkinson's disease (PD) patients who developed the onset of new troublesome dyskinesias after Levodopa-Carbidopa Intestinal Gel (LCIG) initiation. We were…Parkinson’s disease and intermittent hypoxia training: beneficial or harmful?
Objective: To systematically review the scientific evidence for beneficial or harmful effects of intermittent hypoxia that were used in Parkinson’s disease (PD) in clinical and…Effects of safinamide and rasagiline on in vivo glutamate release in 6-OHDA hemilesioned rats
Objective: To investigate the effects of safinamide (saf) and rasagiline on in vivo glutamate (Glu) release in the 6-hydroxydopamine (6-OHDA) hemilesioned rat model of Parkinson’s…PRECISE-PD: From pathophysiology to precision medicine for Parkinson’s disease
Objective: To propose a mechanism-based progression model of Parkinson’s disease (PD) by combining genetic, imaging, and longitudinal clinical data from a large cohort of patients.…Parkinson’s disease Polygenic Risk Factor Scores in Patients with Inflammatory Bowel Disease
Objective: To assess the genetic risk factors for Parkinson’s disease (PD) in a large population of patients with inflammatory bowel disease (IBD), as compared to…Identification of genetic alterations and SNCA mutation in Parkinson’s disease patients of Coimbatore Population, India
Objective: The aim of the study is to analyze the genetic alterations in SNCA gene and dopamine transporter in 22 PD patients of Coimbatore population.…Longitudinal analysis of the modified Hoehn and Yahr disease stage in PD-1101, a Phase 1b clinical study of VY-AADC01
Objective: To describe changes over the first year in disease severity and activities of daily living using modified Hoehn and Yahr (mH&Y) stage and UPDRS…Parkinson’s Disease Treatments and Outcomes: US v Non-US Patients
Objective: To determine if there are differences in treatment patterns and outcomes in US patients, who often must pay for some of their care, and…Longitudinal digital observation of the holistic quality of the life of patients with Parkinson’s disease
Objective: The aim of this study is the development of a digital concept for a longitudinal assessment of quality of life during the various stages…
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