The SUNRISE-PD Study, a clinical trial of AXO-LENTI-PD: a CNS-directed gene therapy for the treatment of Parkinson’s Disease
Objective: This presentation will provide an overview of the design and key objectives of the SUNRISE-PD study. Background: Parkinson’s disease (PD) is caused in part,…Real-life gait performance as a marker for motor fluctuations: the Parkinson@home Validation study
Objective: To assess the feasibility of using real-life gait performance derived from a single wearable as a marker for motor fluctuations in Parkinson’s disease (PD).…Serum mucosal chemokine levels in patients with Parkinson disease.
Objective: To investigate the relationship between mucosal chemokines including CXCL14 and CCL28) and impairment in motor/non-motor function among patients with Parkinson’s disease. Background: Parkinson disease…Skin in the game: Small fiber neuropathy in Parkinson’s disease and atypical parkinsonisms.
Objective: The aim of our study was to compare somatic and autonomic small fiber density, through skin biopsy, in Parkinson's disease (PD) and atypical parkinsonisms…A case of osmotic demyelination syndrome presenting parkinsonism affected by blood alcohol concentration change
Objective: To describe a patient with osmotic myelinolysis caused by change in blood alcohol level who developed acute parkinsonism. Background: Osmotic myelinolysis is an acute,…STN-DBS programing for dyskinesia: a case report
Objective: To investigate the effect of STN stimulation on different types of dyskinesia and programming strategy. Background: Long-term use of levodopa or dopamine agonists often…The long-term effect of continuous apomorphine treatment on camptocormia in Parkinson´s disease: a 24-months longitudinal open, prospective follow-up study
Objective: The aim of the study was to assess the long-term effect of subcutaneous infusions of apomorphine in the treatment of camptocormia in advanced Parkinson's…Parkinsonian syndrome associated to C9orf72 expansion
Objective: To describe a case of parkinsonian syndrome associated to C9Orf72 expansion followed by ALS development Background: C9Orf72 expansions are known to be the most…Deep Brain Stimulation Wash-in/out Periods Quantified using a Palm-Worn Device to Monitor Rigidity
Objective: Characterize the temporal resurgence/amelioration of Parkinsonian rigidity corresponding to withdrawal/application of deep brain stimulation (DBS) therapy. Background: Rigidity is a cardinal symptom of Parkinson’s…Pharmacokinetics of ABBV-951 Following 24-Hour Continuous Subcutaneous Infusion to Arm, Abdomen and Thigh
Objective: Characterize levodopa pharmacokinetics (PK) and safety/tolerability of ABBV-951 in healthy volunteers at 3 different subcutaneous (SC) infusion sites: Arm, Abdomen and Thigh Background: As…
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