Connectivity alterations in dopaminergic and cholinergic networks mediate cognitive performance in patients with Parkinson’s disease: a resting-state fMRI study
Objective: To explore changes in resting-state fMRI (rs-fMRI) functional connectivity networks in PD patients, in areas with prominent dopaminergic and cholinergic innervation. Background: The pathophysiology…Glymphatic system activity in Parkinson’s disease: diffusion tensor image analysis along the perivascular space (DTI‑ALPS)
Objective: We examined the activity of the glymphatic system in patients with Parkinson’s disease using diffusion tensor image analysis along the perivascular space (DTI-ALPS). Background:…Preserved white matter microstructure in Parkinson’s disease patients with levodopa-induced dyskinesia: Evaluation by neurite orientation dispersion and density imaging (NODDI)
Objective: Brain microstructure alteration using MRI in Parkinson's disease (PD) have not been well studied. We analysis the white matter alterations in Parkinson’s disease with…Longitudinal Change of Substantia Nigra Hyperechogenicity in Parkinson’s Disease Cohort
Objective: To analyze whether the size of SN+ is differentially affected depending on disease duration. Secondly to analyze the interaction between a range of clinical…Kick Out PD: Mobility, Quality of Life, and Feasibility Outcomes in a Pilot Study of a PD-Specific Karate Intervention
Objective: To evaluate feasibility of a community-based karate class tailored for individuals with early- to middle-stage Parkinson’s Disease (PD); to assess effect of karate on…Predicting the efficacy of STN-DBS in patients with different Parkinson’s disease motor subtypes by preoperative total and partial levodopa response
Objective: To better investigate the value of the challenge test by introducing total and partial LR, and explain the clinical significance of 30% LR through…Lack of Notable Skin Reactions from a Novel Levodopa/Carbidopa Prodrug after 10 Days of Repeated 24-Hour Continuous Subcutaneous Infusion at the Same Administration Site
Objective: To assess the skin safety and tolerability of 24-hour continuous subcutaneous infusion (CSCI) of ABBV-951. Background: Therapeutic approaches for advanced Parkinson’s disease (aPD) patients…OPICAPONE: REAL WORLD EVIDENCE IN TOLEDO´S MOVEMENT DISORDERS UNIT
Objective: We present a prospective observational-real life study about the use in Movement Disorders Unit´s patients, since its commercialization in Spain (June 2017). Background: The…Vortioxetine treatment of depression in Parkinson’s disease
Objective: To assess efficacy and safety of Vortioxetine in Parkinson’s Disease (PD) patients affected by depression and its effects on motor performance. Background: Depression is…Quercetin Regulates Cadmium Induced Motor Dysfunction in Depletion of Dopamine and its Metabolites at Synapse
Objective: The present study has an attempt to understand cadmium induced alteration in dopamine and associated signaling that causes the motor alterations in rats and…
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