Influence of peripheral immune system on cognitive profile in Parkinson’s disease
Objective: To investigate the influence of the peripheral immune profile in the development of cognitive impairment in PD. Background: Dementia is frequent in advanced Parkinson’s…Clinical Response to 72-h Lumbar CSF Drainage in Idiopathic Normal Pressure Hydrocephalus associated with Parkinsonism: Timing and Correlates
Objective: To evaluate timing and clinical correlates of motor response after 72-h lumbar CSF drainage in patients with Normal Pressure Hydrocephalus (iNPH) associated with parkinsonism.…Parkinson’s Disease Presentation in Calabar, Nigeria
Objective: To create a database and describe the presentation of Parkinson's disease patients at the sole tertiary hospital in Calabar, southern Nigeria. Background: Parkinson's disease…Identifying healthy Parkin mutation carriers based on sensor-based posturography and gait analysis
Objective: To discriminate healthy Parkin mutation carriers from healthy non-mutation carriers using sensor-based motion analysis. Background: Identifying endophenotypes for PD is crucial for testing potential…Stereopsis as a Visual Biomarker for Parkinson’s Disease
Objective: 1): To assess Parkinson’s disease (PD) patients’ stereopsis function using better and more physiologically meaningful tools; 2): To reveal specific eye behaviors of stereoacuity…Serological analysis of circulating Alpha Synuclein protein levels by Surface Plasmon Resonance (SPR) In Parkinson’s disease
Objective: α-synuclein (α-Syn) is a presynaptic protein whose overexpression or misfolding contributes to the pathophysiology of Parkinson’s disease (PD). This study aims to estimate the…Does Anticholinergic Burden Affect the Outcomes in Patients Diagnosed with Parkinson’s Disease?
Objective: To explore the impact of an anticholinergic burden on various outcomes in Parkinson’s disease. Background: Over 600 different medications possess some anticholinergic effect.[1] There…APOmorphine infusion and aMYLoid deposition in Parkinson’s disease (APOMYL): preliminary clinical and amyloid imaging data
Objective: To explore the potential effects of chronic Apomorphine infusion treatment on reducing brain Amyloid-b (Aβ) deposition in Parkinson’s disease (PD). Background: A majority of…The relationship between constipation and alteration of gut microbiota in patients with Parkinson’s disease
Objective: To study compositional and functional differences in the gut microbiota and its products between individuals with PD and matched controls,and these differences are or…Initial Validation of the Cortical Basal ganglia Functional Scale (CBFS) in two international, multicenter cohorts: 4RTNI and PROSPECT
Objective: To assess the validity of a patient/caregiver-reported scale for assessing functional disability in 4R tauopathies. Background: 4R tauopathies (4RT) including progressive supranuclear palsy (PSP),…
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