Quantitative study of subthalamic ERG potassium channels in parkinsonian discharges
Objective: This study describes the role of the subthalamic ERG Potassium (ERG K+) ion channel conductance in cellular excitability in subthalamic nucleus (STN) neurons towards…Does Gait in Real Life differ between People with Parkinson’s Disease and Healthy Controls?
Objective: We investigated whether: 1) gait in daily life differs in people with Parkinson’s disease (PD) compared to healthy controls (HC), and 2) the length…Differential enhancement of ERK, PKA and Ca2+ signaling in direct and indirect striatal neurons of Parkinsonian mice
Objective: To identify cell-specific and dynamical modifications of signaling pathways associated with PD and drug-induced modifications Background: Parkinson's disease (PD) is characterized by severe locomotor…SNCA G51D missense mutation causing juvenile onset Parkinson’s disease
Objective: To report the clinical and genetic features in a Parkinson’s patient with the SNCA G51D missense mutation. Background: α-synuclein (SNCA) gene mutations are recognized…Development of a web-based tool for systematic collection of phenotypes of hereditary movement disorders from medical literature
Objective: To develop a web-based tool to collect phenotypes of heterditary movement disorders. Background: Deep phenotyping, the precise and comprehensive analysis of phenotypic abnormalities, is…Screening of mutations in PARK2 gene and Dopamine levels in Parkinson’s disease (PD) patients in Coimbatore population, India
Objective: The aim of the present study was to perform the mutational screening of PARK2 gene and dopamine level in PD patients of Coimbatore population,…Bilateral Putaminal AAV2-GDNF Delivery the Treatment of Advanced Parkinson’s Disease
Objective: To investigate the safety, tolerability, and early clinical efficacy of escalating doses of AAV2-GDNF delivered into the bilateral putamen of patients with advanced PD…What patients need – a qualitative analysis of consultations prior to deep brain stimulation in patients with Parkinson’s disease
Objective: To evaluate the different needs of patients with Parkinson’s disease (PD) prior to deep brain stimulation (DBS). Background: DBS is a well established and…A Smart Device System (Wearable technology band) to Identify New Phenotypical Characteristics in Parkinson‘s disease patients
Objective: To develop methods for analyzes and monitor of gait data via smart device system and identify new phenotypical characteristics in PD patients. Background: Parkinson's…Complex Training of Balance in Parkinson’s Disease
Objective: To study the effect of biofeedback (BFB) and balance training in patients with Parkinson disease (PD). Background: Gait and balance disorders, characterized by freezing…
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