Manganese-induced Parkinsonism Vs Rotenone-induced Parkinsonism: Animal Life Matters!
Objective: To evaluate the Parkinsonism mimicking potential of MnCl2 in an experimental rat model.To compare the destructive effect of MnCl2 with rotenone by performing behavioral,…Integrating Parkinson’s Plus Cohorts into the Global Parkinson’s Genetics Program
Objective: To integrate Parkinson’s Plus Cohorts into the Global Parkinson’s Genetics Program (GP2) and design a dictionary of data to be collected. Background: GP2 is…Disease-related comprehensive motor pattern derived from 2D single RGB video as a biomarker for early and prodromal Parkinson disease
Objective: This study aims to develop a disease-related motor pattern from a single 2D RGB video as a biomarker for early diagnosis and monitoring of…Comparison of Age, Cognitive, Autonomic, and Motor Testing between Serotonergic vs Idiopathic REM-Sleep Behavior Disorder
Objective: To compare the age, cognitive, autonomic, and motor function of REM-Sleep Behavior Disorder (RBD) patients amongst those who believe their symptoms were triggered by…Loneliness Relates to Gait Over Other Features of Parkinsonism
Objective: To assess the relationship between loneliness and facets of parkinsonism in community-based samples. Background: Loneliness increases the risk of mortality, dementia, depression, and motor…Cross-Omics Clustering Identifies Common Molecular Patterns in Parkinson’s Disease
Objective: Uncover novel molecular signatures to define Parkinson's disease (PD) patients' clusters using multi-omics integration and evaluate clinical and neuroimaging data. Background: PD is a…The Feasibility and Practical utility of Virtual Visits for Patients with Parkinson’s disease in Different World Regions
Objective: To investigate the feasibility and efficacy of virtual visits (TM) for Parkinson's Disease (PD) compared to in-person visits in different World Health Organization (WHO)…Lysosomal network defects in parkinsonian patients carrying rare variants in lysosomal hydrolytic enzyme genes
Objective: Functional validation of rare variants of lysosomal genes potentially associated with early onset Parkinson's disease (EOPD) Background: The genetic load in EOPD is high;…Can Heterozygous Autosomal Recessive Mutations Cause Neurological Disease?
Objective: To highlight the significance of heterozygous PLA2G6 and PRKN gene mutations in causing parkinsonism. Background: We report our observations in two families with multiple…Misdiagnosing Movement Disorders on a Terciary Academic Center in the Caribbean: A Series of Cases
Objective: To report 10 movement disorder cases misdiagnosed by general neurologists as another disorder or a different category of movement disorder. Background: The misdiagnosis of…
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