RESET-DBS: An exploratory study on the safety and efficacy of personalized burst-patterned deep brain stimulation (DBS) in Parkinson’s Disease (PD)
Objective: To assess the safety and efficacy of a personalized burst patterned STN-DBS (bDBS) vs. conventional high-frequency DBS (cDBS). Background: A physiological rationale suggests possible…Investigation of the Mendelian contribution of parkinsonism associated genes to Parkinson’s disease
Objective: To explore the diagnostic yield and clinical relevance of Parkinsonism associated genes (PAGs) screening in Parkinson’s disease (PD). Background: The contribution of well-known PD…Incidence and Outcomes of Hip Fractures in Parkinsonism vs Non-Parkinson Population: A Systematic Review of the Literature
Objective: To assess hip fractures incidence in Parkinsonism patients and assess their outcome. Background: Parkinson's disease is associated with gait disturbance, postural instability, and increased…Multiple System Atrophy Without Dysautonomia
Objective: TTo investigate the frequency, clinical characteristics, and disease trajectory of patients with MSA presenting without dysautonomia and to compare their course with patients showing…A Patient-Directed AI-Enabled Platform for Continuous Personalised Parkinson’s Management
Objective: To describe the co-design and staged evaluation of a novel AI-enabled digital health platform for Parkinson’s where structured patient and clinician feedback informs iterative…Heart Rate Variability in Early Parkinson’s Disease
Objective: This study aimed to investigate the clinical relevance of heart rate variability (HRV), which may indicate underlying autonomic nervous system activity, in patients with…The influence of Parkinson’s disease duration on perceived quality of inpatient care
Objective: There are currently no disease-modifying therapies for persons with Parkinson’s disease (PD), and progressive symptoms contribute to increased risk of hospitalization, particularly in the…Association of Glymphatic Flow at Diffusion Tensor Image with Motor Symptoms and Striatal Dopamine Degeneration in Parkinson’s Disease
Objective: This study aimed to investigate the association between the diffusion tensor image (DTI) analysis along the perivascular space (ALPS) index, dopamine transporter (DAT) availability…Delayed-Onset Rapidly Progressive Parkinsonism After BCMA×CD3 Bispecific Antibody Therapy: A Case Report
Objective: To describe a delayed-onset rapidly progressive parkinsonian syndrome with encephalopathy following BCMA×CD3 bispecific antibody therapy. Background: B-cell maturation antigen (BCMA) × CD3 bispecific antibodies…Development of a Nationwide Parkinson’s Disease Cohort in Korea: Toward an Ethnicity-Specific Precision Medicine Platform
Objective: To establish and longitudinally expand a nationwide Parkinson’s disease (PD) cohort in Korea (K-PD cohort) and develop an ethnicity-specific precision medicine platform integrating clinical,…
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