The NIC-PD-study –A randomized, placebo-controlled, double-blind, multi-centre trial to assess the disease-modifying potential of transdermal nicotine in early Parkinson‘s disease in Germany and N. America
Objective: To evaluate the disease modifying potential of transdermal (TD) nicotine in early Parkinson’s disease (PD). For this explanatory purpose, the primary endpoint was the…Effects of Expiratory Muscle Strength Training and Voice Therapy on Parkinsonian Speech
Objective: The current study compared the effects of expiratory muscle strength training (EMST) and EMST plus voice therapy (VT) on speech loudness and intelligibility of…Frequency-dependent effects of subthalamic deep brain stimulation on motor symptoms in Parkinson’s disease
Objective: This study aims to investigate whether low-frequency stimulation (LFS) (100Hz, mostly 130 or 150 Hz) in deep brain stimulation (DBS) targeting subthalamic nucleus (STN).…Programming for Freezing of gait after Bilateral Subthalamic Nucleus Deep Brain Stimulation for Parkinson’s Disease
Objective: Freezing of gait (FOG) is a common gait disorder in Parkinson's disease (PD). In this study, we will adjust programming for patients with FOG…Toe dystonia in Parkinson’s disease: Impact of subthalamic nucleus deep brain stimulation
Objective: To analyze the prevalence and the evolution of toe dystonia in parkinson's disease (PD) patients candidate to subthalamic nucleus deep brain stimulation (STN-DBS). Background:…Mortality from Parkinson’s disease in China: Findings from a Ten-year follow up study in Shanghai
Objective: To examine the outcome, including overall and cause-specific mortality, of PD patients subsequent to 10 years of surveillance in Shanghai, China. This is an…Relationship of 10-Meter Walk Test to balance performance in Parkinson’s disease patients as a predictor of falls
Objective: This study aimed to clarify the relationship between the 10-Meter Walk Test (10-MWT) and balance performance in PD. Background: Patients with Parkinson's disease (PD)…Cerebral and pulmonary thromboembolism in a patient with hyperhomocystinemia treated with high dose levodopa/carbidopa intestinal gel
Objective: We report a case that developed cerebral and pulmonary thromboembolism during 24-hour levodopa/carbidopa intestinal gel (LCIG) infusion. Background: LCIG is a therapeutic option in…Toxin-induced Parkinsonism: A report of two patients
Objective: To highlight the presentation of parkinsonism caused by acute and chronic exposure to carbon monoxide(CO). Background: Toxin-induced parkinsonism is not uncommon. One of the…Immunological causes of atypical parkinsonism
Objective: To study the clinical and biochemical features of atypical parkinsonism. Evaluate results of the immune-mediated treatment Background: Atypical parkinsonism is a heterogeneous group of…
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