A randomized clinical trial of multimodal balance training with rhythmical cues: effects on freezing of gait in Parkinson’s disease
Objective: To investigate whether the multimodal training is more effective in improving balance and gait in freezers versus non-freezers. Background: Non-pharmacological interventions are increasingly used…The evaluation of exosomes as a biomarker of Parkinson’s disease
Objective: This study is aimed to investigate whether the number and the contents of serum exosomes can serve as a useful biomarker for the diagnosis…Open-Label Study of Pimavanserin Patients With Comorbid Parkinson’s Disease and Depression
Objective: We are assessing use of pimavanserin (PIM) for treatment of depression in adults with PD. Background: Depression occurs in ~50% of Parkinson’s disease (PD)…The relationship between the motor onset and the asymmetry of motor symptoms in patients with Parkinson’s Disease
Objective: The objective of our research was to study the relationship between the motor onset and the asymmetry of motor symptoms in patients with Parkinson’s…The association parkinsonism and psychotic symptom in neurosyphilis
Objective: To report the cases of neurosyphilis revealed by the association parkinsonism and psychotic symptom. Background: The NS is the "great imitator" because it can…Variants in the beta-Glucocerebrosidase A (GBA) gene in German patients with Parkinson´s disease
Objective: To characterize GBA variants in a cohort of German patients with PD. Background: GBA encodes the lysosomal enzyme beta-glucocerebrosidase A. GBA mutations cause the lysosomal…Effect of polygenic load on striatal dopaminergic deterioration in Parkinson’s disease
Objective: To investigate the longitudinal association between PD-associated polygenic load and the striatal dopaminergic activity using 123I-N-3-fluoropropyl-2-beta-carboxymethoxy-3beta-(4-iodophenyl) nortropane (123I-FP-CIT) single photon emission computed tomography (SPECT).…Rapidly onset progressive generalised dystonia parkinsonism in a young Indian male with rare FBXO 7 genetic mutation
Objective: To describe a rare case of rapidly progressive generalized dystonia parkinsonism due to FBXO7 gene mutation. Background: Parkinson’s disease is a neurodegenerative disorder of…Severity of REM sleep without atonia (RSWA) correlates with cognitive functions in patients with REM sleep behaviour disorder (RBD)
Objective: to assess the correlations between the severity of RSWA and cognitive functions in patients with RBD, both isolated (iRBD) and associated to Parkinson’s Disease…The influence of relationship quality on health-related quality of life when coping with Parkinson’s disease: a mediation analysis
Objective: To explore motor and non-motor symptoms (NMS) influence on relationship quality (mutuality) and health-related quality of life (HRQoL) when one in the dyad is…
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