Retrospective study on a cohort of 285 PD patients: Does the side of onset influence the global clinical phenotype?
Objective: To describe demographic and clinical characteristics of a cohort of 285 consecutive PD patients and to understand the phenotypic differences of right onset (RPD)…Quailty of life and Parkinson’s disease: Philippine translation and validation of the Parkinson’s disease questionnaire
Objective: This study translated PDQ-39 into the Filipino language as the Philippine-PDQ-39 (P-PDQ-39), and used it to assess the quality of life of Filipino patients…Treadmill-based gait analysis for gait abnormality of Parkinson disease
Objective: To compare gait characteristics from walking on a treadmill machine between Parkinson's disease (PD) patients and controls Background: Gait disturbance is gradually worsened as…NMSQ Application: A New Way to Access Non-Motor Symptoms in Patients with Parkinson’s Disease
Objective: To investigate the utility and satisfaction of non-motor symptoms questionnaire (NMSQ) application in Thai patients with Parkinson’s disease (PD) in clinical practice. Background: Non-motor…Transcranial magnetic stimulation increases cognition globally and longitudinally in Parkinson’s disease
Objective: Using intermittent “theta burst” transcranial magnetic stimulation (iTBS) over the left dorsolateral prefrontal cortex (DLPFC) to assess the potential of long-term improvements in cognitive…Cognitive Impairment and Depression in Patients with Parkinson’s Disease
Objective: To evaluate cognitive impairment and depression in patients with Parkinson's Disease (PD) and its relationship. Background: Patients with Parkinson's disease are prone to cognitive…Knockdown of eEF1A2 reduced neuronal survival in a SH-SY5Y cellular model of Parkinson’s disease through the PI3K/Akt/mTOR pathway
Objective: To investigate whether eEF1A2 promotes neuronal survival through PI3K/Akt/mTOR pathway in a toxin-induced Parkinson’s disease model. Background: Parkinson’s disease is a common neurodegenerative disorder…Variants in MCCC1/LAMP3 and DGKQ Identified Through GWAS are Not Associated with PD in a Malaysian Malay Cohort
Objective: To investigate the association between variants in MCCC1/LAMP3 (rs12637471, rs12493050, rs10513789) and DGKQ (rs11248060) with PD in a Malay cohort. Background: Previous genome-wide association…Daughter’s ataxia reveals father’s genetic Parkinsonism. The first reported case of Spinocerebellar ataxia -15 presenting with levodopa responsive hemi Parkinsonism
Objective: A 38 year old Australian florist of Anglo-Celtic origin described two years of difficulty using his right hand with associated sensory disturbance attributed initially…Non-invasive, automated corneal nerve quantification reveals neurodegeneration in Parkinson’s disease: A potential novel imaging biomarker
Objective: The aim of the study is to use automated analysis of corneal confocal microscopy (CCM) images to allow rapid and reliable quantification of corneal…
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