Alterations of cortical metabotropic glutamate receptor-mediated signaling in patients with Parkinson’s disease
Objective: To evaluate expression of brain metabotropic glutamatergic receptor 5 and the relationship with clinical measures in Parkinson’s disease patients. Background: Metabotropic glutamate receptor 5…The study of 18F-FDG PET / CT imaging in the value on Parkinson’s disease
Objective: In this study,we were to investigate imaging characteristics of 18F-FDG PET/CT in patients with Parkinson's disease (PD), and explore its value on PD. Background:…Skin Deposition of Pathological Alpha-Synuclein in Idiopathic REM-sleep Behavior Disorder and Parkinsonism
Objective: To assess cutaneous pathological Alpha-syn deposition in patients with iRBD, PD, atypical parkinsonism and controls. Background: Peripheral autonomic neurodegeneration may occur in early stages…Multimorbidity predicts quality of life but not motor severity in early Parkinson’s disease
Objective: To explore the associations between multimorbidity, severity of motor symptoms, and quality of life (QoL) in people with early PD. Background: Multimorbidity is defined…Nonlinearities in outcome-specific hazard of motor and nonmotor long-term complications of Parkinson’s disease
Objective: To estimate the specific hazard of motor and nonmotor milestones of Parkinson's disease (PD) progression in the long term. Background: Parkinson’s disease greatly varies…New evidence for thalamic dysfunction in Parkinsonian rats
Objective: Abnormal oscillatory activity within the cortico-basal ganglia (BG)-thalamo-cortical circuit has been observed in Parkinsonian state, especially of β and γ bands (βB and γB).…Insulin degrading enzyme, a novel key protein against alpha-synuclein oligomers formation?
Objective: The objective of this work is to study the interaction between α-synuclein and the insulin degrading enzyme in the pancreas of subjects with synucleinopathies.…Protective effects of Mucuna pruriens seed on rat brain: A therapeutic potential drug for Parkinson’s disease
Objective: Objective of present study was evaluate neuroprotective and antiparkinson effects of Mp seed extract on Parkinsons brain of rats. Background: Parkinson’s disease (PD) is…Neuropathological correlates of psychiatric disorders in PD
Objective: To test the hypothesis that neuropsychiatric symptoms (NPS) in PD are associated with histopathologically confirmed neuronal loss and gliosis (NLG) in the locus coeruleus…Impact of postural stability estimation in HY scale. (Pull test Vs. limits of stability assessment)
Objective: Stability evaluation is of much value for staging the disease according to the Hoehn and Yahr (HY) scale. We propose to correlate a dynamic…
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