Stabile cognitive profile one year after subthalamic nucleus deep brain stimulation in patients with advanced Parkinson’s disease
Objective: To prospectively study the cognitive functions in Parkinson’s disease (PD) patients treated with deep brain stimulation of subthalamic nucleus (STN DBS). Background: STN DBS is a…How common are the genomic rearrangements among possibly autosomal recessive PD cases in Turkey?
Objective: In this study, we aimed to investigate the frequency and phenotypical features in a subset of early-onset Parkinson’s disease (EO-PD) (age-at-onset ≤45 years) patients due…Alterations in lipid metabolism modify GBA1-mediated neurodegeneration in a Drosophila model of Parkinson’s disease
Objective: To understand how glucocerebrosidase (GBA1) mutations increase susceptibility to Parkinson's disease (PD). Background: Our understanding of the pathogenesis PD remains limited, and currently no…Impulse Control Disorders in Parkinson’s Disease: Prevalence and Clinical Features in the Rush University Movement Disorders Clinic
Objective: Investigate the prevalence and characteristics of Impulse Control Disorders (ICDs) in the PD population as compared to non-ICD patients in the Rush University Movement Disorders (RUMD) database.…Distinguishing Subclinical Postural Instability in Early-stage Parkinson disease and postural instability of normal elderly using Sensory Organization Test and Limit of Stability
Objective: To distinguish postural instability differences in Parkisnon disease patients and normal elderly patients with computerized dynamic posturography Background: Postural instability is a core symptom…Disease modeling for Perry syndrome using patient induced pluripotent stem cells
Objective: To develop a novel model of Perry syndrome using induced pluripotent stem cell (iPSC)-derived neurons. Background: Perry syndrome is a rare autosomal dominant disorder…Death in patients with Parkinson’s disease – an observational study
Objective: We aimed to analyse the major cause and contributory reasons for death in patients with Parkinson’s disease (PD) who were known to our PD…Disease severity is not predictive of the dose required for apomorphine sublingual film (APL-130277) to convert a patient with Parkinson’s disease(PD) from OFF to fully ON: Preliminary Results from a Phase III Study
Objective: To determine if baseline disease severity could be correlated to the effective dose of APL-130277 that was required to turn a patient with PD…Alternations of Metabolic Profile and Kynurenine Metabolism in the Plasma of Parkinson’s Disease
Objective: The purpose of this study was to identify potential plasma metabolic biomarkers for Parkinson’s disease (PD) Background: PD, characterized by a slowness of movement…Study Design for a Multi-Modal Approach to Understanding Parkinson’s Disease: The Personalized Parkinson Project
Objective: We aim to create a longitudinal dataset of clinical, molecular, imaging, and continuous wearable sensor-based data from a representative Parkinson’s disease (PD) cohort. Data…
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