Group meetings for newly diagnosed Parkinson’s disease patients and their spouses: A preliminary experience
Objective: To estimate the contribution of a group meeting for newly diagnosed PD patients and their spouses. Background: Parkinson's disease (PD) is a common neurodegenerative…A validation study of a smartphone-based finger tapping application for quantitative assessment of bradykinesia in Parkinson’s disease
Objective: We developed an application of smartphone tapper (SmpT) and sought to determine whether SmpT is applicable for clinical purpose by comparing SmpT parameters to…A rare genetic transcriptomopathy syndrome involving TAF1 leading to insights into more common neurologic disorders, including X-linked dystonia-parkinsonism (XDP)
Objective: We set out to discover the genetic basis of an X-linked genetic syndrome presenting with global developmental delay, intellectual disability, characteristic facial dysmorphology, generalized…C9ORF72 intermediate repeat copies as a rare genetic cause of atypical Parkinsonian syndromes or Parkinson’s disease complicated by psychosis in a Sardinian population
Objective: To screen for the presence of C9ORF72 repeat expansions in patients affected by atypical parkinsonism syndromes and PD complicated by psychosis or dementia, and…Clinical profile of Wilson’s disease at Yangon General Hospital, Myanmar
Objective: To evaluate clinical, biochemical and imaging profile of patients with Wilson's Disease (WD). Background: There was no reported case series of WD in Myanmar.This…Increased anti-MAG autoantibodies titers in Parkinson’s disease
Objective: To search for biomarkers of neurodegenerative process in Parkinson's disease (PD).There is emerging evidence that humoral response may be involved in the pathogenesis and…Hyperin inhibits lipopolysaccharide-induced microglia activation through p38 and NFκB signaling
Objective: In this study, we aimed to investigate hyperin's potentiality in inhibition of neuroinflammation. Background: Hyperin is an active compound isolated from Rhododendron brachycarpum G.…Constipation in early de novo Parkinson’s disease: Prevalence and correlates with clinical features, imaging and non-imaging biomarkers
Objective: To explore the association between constipation and clinical features, imaging and non-imaging biomarkers in early de novo (untreated) Parkinson's disease (PD) patients. Background: Constipation…Diffusion tensor imaging biomarkers of nigrostriatal neurodegeneration in early Parkinson’s disease
Objective: Identify magnetic resonance imaging (MRI) biomarkers of nigrostriatal neurodegeneration in early-stage drug-naïve Parkinson's disease (PD). Background: Diffusion tensor imaging (DTI) is an MRI technique…Is levodopa-induced dyskinesia in Parkinson’s disease associated with increased blood brain barrier permeability and volumetric changes?
Objective: The aim of this study was to explore the angiogenetic hypothesis for Levodopa-induced-dyskinesia (LID) using advanced MRI methods in patients with Parkinson's disease (PD).…
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