Histone deacetylase 4 is regulated by microRNA 128 in SH-SY5Y cells of Parkinson’s disease
Objective: To explore the mechanisms and regulating effects of microRNA 128 in Parkinson's disease (PD). Background: PD is the second common progressive neurodegenerative disorder characterized…Alterations in 14-3-3 protein phosphorylation as a biomarker for neurodegeneration
Objective: To examine whether 14-3-3 phosphorylation is altered in Parkinson's disease and other neurodegenerative disorders. Background: 14-3-3 proteins are a highly conserved family of proteins…Effects of age and gender on brainstem MR-planimetry
Objective: To evaluate age- and gender effects on brainstem MR-planimetric measures. (1,2). Background: Brainstem planimetry has been successfully applied to differentiate Progressive Supranuclear Palsy (PSP)…Arterial spin labeling perfusion MRI compensate for other diagnostic tools in evaluation of Parkinson’s disease with dementia
Objective: To test usefulness of arterial spin labeling (ASL) perfusion MRI for diagnoses of Parkinson's disease (PD) with dementia. Background: Dopamine transporter (DAT) images may…Neural mechanisms underlying step initiation failure in patients with Parkinson’s disease and freezing of gait
Objective: To investigate the neural mechanisms underlying gait initiation failure in Parkinson's disease patients with Freezing of Gait. Background: Freezing of Gait (FOG) is a…Movement related beta oscillatory activity during self-paced wrist movement in the human subthalamic nucleus
Objective: To explore voluntary movement related neuronal activity in the subthalamic nucleus in patients with Parkinson's disease (PD). Background: How the human basal ganglia processes…Increased cortical control of gait in patients with Parkinson’s disease and freezing of gait
Objective: To determine structural connectivity between the mesencephalic locomotor region (MLR) and the supplementary motor area (SMA) in freezers compared to non-freezers. Background: Freezing of…Spectral analysis of rapid eye movement (REM) sleep as a potential marker of neurodegenerative disease in REM sleep behavior disorder
Objective: To investigate whether spectral analysis at baseline in rapid eye movement (REM) sleep can differentiate patients with REM sleep behavior disorder (RBD) who will…Catechol-o-methyltransferase Val158Met polymorphism influences prefrontal executive function in early Parkinson’s disease
Objective: The Catechol-O-Methyltransferase (COMT) Val158Met polymorphism has been proposed to be associated with increased risk of PD and have a specific impact on dopamine-mediated prefrontal…Longterm outcome of cognition following subthalamic deep brain stimulation in Parkinson´s disease
Objective: Longterm, “real-life” assessment of cognitive evolution following subthalamic (STN) deep brain stimulation (DBS) in patients suffering from Parkinson´s disease. Background: Anecdotal reports have speculated…
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